BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis - Canver, Matthew C.; Smith, Elenoe C.; Sher, Falak; Pinello, Luca; Sanjana, Neville E.; Shalem, Ophir; Chen, Diane D.; Schupp, Patrick G.; Vinjamur, Divya S.; Garcia, Sara P.; Luc, Sidinh; Kurita, Ryo; et al. (Nature (London), 2015)
Keywords: 13/100; 13/109; 13/31; 38/22; 38/70; 38/77; 38/88; 45/23; 49/47; 631/1647/1511; 631/208/200; 631/337/572/2102; 64/60; 692/308/2056; Animals; Base Sequence; Carrier Proteins - genetics; Cells, Cultured; Clustered Regularly Interspaced Short Palindromic Repeats - genetics; CRISPR-Associated Proteins - metabolism; CRISPR-Cas Systems - genetics; DNA methylation; DNA-Binding Proteins; Enhancer Elements, Genetic - genetics; Erythroblasts - metabolism; Fetal Hemoglobin - genetics; Gene expression; Genetic diversity; Genetic Engineering; Genome - genetics; Genomes; Genomics; Humanities and Social Sciences; Humans; Methods; Mice; Molecular Sequence Data; multidisciplinary; Mutagenesis; Mutagenesis - genetics; Nuclear Proteins - genetics; Organ Specificity; Physiological aspects; Repressor Proteins; Reproducibility of Results; RNA, Guide, CRISPR-Cas Systems - genetics; Science; Species Specificity; Studies