Reduction of endoplasmic reticulum- mitochondria interactions in beta cells from patients with type 2 diabetes - Thivolet, Charles; Vial, Guillaume; Cassel, Romeo; Rieusset, Jennifer; Madec, Anne-Marie (PloS one, 2017)
Keywords: Adult; Apoptosis; Assaying; Beta cells; Biology and Life Sciences; Biosynthesis; Blood & organ donations; Cells, Cultured; Diabetes; Diabetes mellitus; Diabetes Mellitus, Type 2 - metabolism; Diabetics; Endocrinology; Endoplasmic reticulum; Endoplasmic Reticulum - metabolism; Female; Fluorescent Antibody Technique; Gene expression; Glucose; Health aspects; Humans; Immunofluorescence; In Situ Hybridization; In vitro methods and tests; Inositol 1,4,5-trisphosphate receptors; Inositol 1,4,5-Trisphosphate Receptors - metabolism; Insulin; Insulin resistance; Insulin secretion; Insulin-Secreting Cells - metabolism; Intervention; Laboratories; Life Sciences; Male; Medicine and Health Sciences; Membranes; Middle Aged; Mitochondria; Mitochondria - metabolism; Mitochondrial Membranes - metabolism; Morphology; mRNA; Organ donors; Organelles; Palmitic acid; Pancreas; Pancreatic beta cells; Patients; Proteins; Proximity; Real-Time Polymerase Chain Reaction; Reduction; Research and Analysis Methods; Rodents; Tethering; Transit; Type 2 diabetes; Young Adult