Sequential assembly of cell-laden hydrogel constructs to engineer vascular-like microchannels

• Published in: Biotechnology and bioengineering Vol. 108; no. 7; pp. 1693 - 1703
• Main Authors: Du, Yanan, Ghodousi, Majid, Qi, Hao, Haas, Nikhil, Xiao, Wenqian, Khademhosseini, Ali
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc., A Wiley Company 01.07.2011; Wiley; Wiley Subscription Services, Inc
• Subjects: Animals; Architecture; Assembly; biofabrication; Biological and medical sciences; Biomedical research; biomimetic; Biomimetics; Biotechnology; Cell Survival; Cells; Cells, Cultured; Construction; Construction costs; directed assembly; Endothelial Cells - physiology; Fundamental and applied biological sciences. Psychology; Health. Pharmaceutical industry; Humans; Hydrogel, Polyethylene Glycol Dimethacrylate; Hydrogels; Industrial applications and implications. Economical aspects; Mice; Microchannels; microengineered hydrogel; Microgels; Microvessels; Miscellaneous; Myocytes, Smooth Muscle - physiology; Three dimensional; Tissue engineering; Tissue Engineering - methods; vascular constructs; Reconstruction; microengineered hydrogel; Biomimetics; Tissue engineering; Blood vessel; Network; biomimetic; biofabrication; Hydrogel; directed assembly; vascular constructs; Biomedical engineering

Microscale technologies, such as microfluidic systems, provide powerful tools for building biomimetic vascular‐like structures for tissue engineering or in vitro tissue models. Recently, modular approaches have emerged as attractive approaches in tissue engineering to achieve precisely controlled ar...