临床药师参与肾移植术后合并肠结核患者抗结核治疗的药学实践

目的:探讨临床药师对肾移植术后合并肠结核患者抗结核治疗开展药学监护的实践。方法:临床药师通过参与1例肾移植术后合并肠结核患者抗结核治疗方案的制订,提供药学服务,从药物选择、药品相互作用及不良反应等方面分析药物治疗的合理性。结果:医院各科室、临床医师、临床药师加强合作,制订并不断改善患者的抗结核治疗方案,入院第15日,患者症状好转;第16日,实验室检查结果显示,患者移植肾情况差,血肌酐持续不降,但患者拒绝行血液透析治疗;第19日,患者腹部一般情况好,检测他克莫司的血药谷浓度为4.4 ng/ml,患者及家属拒绝增加他克莫司的剂量;第23日,患者病情突变,积极抢救治疗;第24日,经积极治疗患者病情仍...

Full description

Saved in:
Bibliographic Details
Published in中国医院用药评价与分析 Vol. 17; no. 7; pp. 985 - 988
Main Author 张怡 李兵 李美月
Format Journal Article
LanguageChinese
Published 东莞康华医院药剂科,广东 东莞,523080 2017
Subjects
Online AccessGet full text
ISSN1672-2124
DOI10.14009/j.issn.1672-2124.2017.07.041

Cover

Loading…
More Information
Summary:目的:探讨临床药师对肾移植术后合并肠结核患者抗结核治疗开展药学监护的实践。方法:临床药师通过参与1例肾移植术后合并肠结核患者抗结核治疗方案的制订,提供药学服务,从药物选择、药品相互作用及不良反应等方面分析药物治疗的合理性。结果:医院各科室、临床医师、临床药师加强合作,制订并不断改善患者的抗结核治疗方案,入院第15日,患者症状好转;第16日,实验室检查结果显示,患者移植肾情况差,血肌酐持续不降,但患者拒绝行血液透析治疗;第19日,患者腹部一般情况好,检测他克莫司的血药谷浓度为4.4 ng/ml,患者及家属拒绝增加他克莫司的剂量;第23日,患者病情突变,积极抢救治疗;第24日,经积极治疗患者病情仍未缓解,建议转重症加强护理病房,患者及家属拒绝,放弃治疗自动出院。结论:肾移植术后合并肠结核患者抗结核治疗应结合患者基础情况,从药物抗菌活性、相互作用、不良反应等方面综合考虑,临床药师积极参与临床药物治疗过程,协助临床医师制订和完善了个体化治疗方案,促进了临床合理用药。
Bibliography:ZHANG Yi, LI Bing, LI Meiyue (Dept. of Pharmacy, Dongguan Kanghua Hospital, Guangdong Dongguan 523080, China)
Clinical pharmacists; Renal transplantion; Immunosuppressive agents; Anti tuberculosis treatment; Drug interactions
OBJECTIVE: To probe into the pharmaceutical care for one patient with intestinal tuberculosis after renal transplantion in anti tuberculosis treatment by clinical pharmacists. METHODS: Through participating into the formulation of anti tuberculosis treatment and pharmaceutical care for one patient with intestinal tuberculosis after renal transplantion,the clinical pharmacists analyzed the rationality of medication treatment from the aspects of drug selection,interaction and adverse drug reactions,etc. RESULTS: Different departments,clinicians and clinical pharmacists cooperated with each other,formulated and improve continuously patient's anti tuberculosis treatment,the patient was getting better in the fifteenth day after hospitalization. According to laboratory test results in the sixtee
ISSN:1672-2124
DOI:10.14009/j.issn.1672-2124.2017.07.041