Enhanced cell proliferation and osteogenic differentiation in electrospun PLGA/hydroxyapatite nanofibre scaffolds incorporated with graphene oxide

• Published in: PloS one Vol. 12; no. 11; p. e0188352
• Main Authors: Fu, Chuan, Bai, Haotian, Zhu, Jiaqi, Niu, Zhihao, Wang, Yu, Li, Jianan, Yang, Xiaoyu, Bai, Yunshen
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 29.11.2017; Public Library of Science (PLoS)
• Subjects: 3T3 Cells; Adsorption; Animals; Biology and Life Sciences; Cell Differentiation; Cell Proliferation; Durapatite; Engineering and Technology; Graphite - chemistry; Lactic Acid; Mice; Nanofibers; Nuclear matrix; Osteogenesis - physiology; Physical Sciences; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Properties; Tensile Strength; Tissue engineering; Tissue Scaffolds; China

One of the goals of bone tissue engineering is to mimic native ECM in architecture and function, creating scaffolds with excellent biocompatibility, osteoinductive ability and mechanical properties. The aim of this study was to fabricate nanofibrous matrices by electrospinning a blend of poly (L-lac...