Age-dependent changes in the neural correlates of force modulation: An fMRI study

• Published in: Neurobiology of aging Vol. 29; no. 9; pp. 1434 - 1446
• Main Authors: Ward, Nick S., Swayne, Orlando B.C., Newton, Jennifer M.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.09.2008; Elsevier
• Subjects: Adult; Aged; Aging; Aging - physiology; BOLD; Dominant; Evoked Potentials, Motor - physiology; Female; fMRI; Hand grip; Hand Strength - physiology; Humans; Internal Medicine; Magnetic Resonance Imaging; Male; Middle Aged; Motor Cortex - physiology; Motor system; Muscle Contraction - physiology; Neurology; Non-dominant; Statistics as Topic; Stress, Mechanical; Task Performance and Analysis; fMRI; Non-dominant; Hand grip; Aging; BOLD; Dominant; Motor system

Functional imaging studies in humans have demonstrated widespread age-related changes in cortical motor networks. However, the relative contribution of cortical regions during motor performance varies not only with age but with task parameters. In this study, we investigated whether motor system act...