Elevated levels of 3-nitrotyrosine in brain from subjects with amnestic mild cognitive impairment: Implications for the role of nitration in the progression of Alzheimer's disease - Butterfield, D. Allan; Reed, Tanea T.; Perluigi, Marzia; De Marco, Carlo; Coccia, Raffaella; Keller, Jeffrey N.; Markesbery, William R.; Sultana, Rukhsana (Brain research, 2007)
Keywords: Aged, 80 and over; Alzheimer Disease - genetics; Alzheimer Disease - metabolism; Alzheimer Disease - physiopathology; Alzheimer's disease; Amnesia - diagnosis; Amnesia - metabolism; Amnesia - physiopathology; Biological and medical sciences; Biomarkers - analysis; Biomarkers - metabolism; Brain - metabolism; Brain - physiopathology; Cognition Disorders - diagnosis; Cognition Disorders - metabolism; Cognition Disorders - physiopathology; Disease Progression; Disorders of higher nervous function. Focal brain diseases. Central vestibular syndrome and deafness. Brain stem syndromes; Early Diagnosis; Female; Geriatrics; Hippocampus; Hippocampus - metabolism; Hippocampus - physiopathology; Humans; Immunohistochemistry; Inferior parietal lobule; Male; Medical sciences; Mild cognitive impairment; Nerve Tissue Proteins - metabolism; Nervous system (semeiology, syndromes); Neurology; Nitrates - metabolism; Nitrosative stress; Oxidative Stress - physiology; Parietal Lobe - metabolism; Parietal Lobe - physiopathology; Predictive Value of Tests; Prognosis; Protein nitration; Psychology. Psychoanalysis. Psychiatry; Psychopathology. Psychiatry; Tyrosine - analogs & derivatives; Tyrosine - analysis; Tyrosine - metabolism; Up-Regulation - physiology; Inferior parietal lobule; Mild cognitive impairment; Nitrosative stress; Alzheimer's disease; Protein nitration; Hippocampus; Human; Memory disorder; Nitration; Nervous system diseases; Cognitive disorder; Alzheimer disease; Central nervous system; Protein; Stress; Cerebral disorder; Central nervous system disease; Mild cognitive impairment Nitrosative stress Protein nitration Hippocampus Inferior parietal lobule Alzheimer's disease; Degenerative disease; mild cognitive impairment; Parietal lobe; Amnesia; Neurological disorder