Discovery and mechanism of intestinal bacteria in enzymatic cleavage of C–C glycosidic bonds

• Published in: Applied microbiology and biotechnology Vol. 104; no. 5; pp. 1883 - 1890
• Main Authors: Wei, Bin, Wang, Ya-Kun, Qiu, Wen-Hui, Wang, Si-Jia, Wu, Yue-Hong, Xu, Xue-Wei, Wang, Hong
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.03.2020; Springer; Springer Nature B.V
• Subjects: acid hydrolysis; Animals; Bacteria; Bacteria - enzymology; Bacteria - isolation & purification; Bacteria - metabolism; Bacterial Proteins - genetics; Bacterial Proteins - metabolism; bioactive properties; Biomedical and Life Sciences; Biotechnology; Biotransformation; Carbon; chemical bonding; Cleavage; Covalent bonds; Deglycosylation; enzymatic treatment; Enzymes; Feces; Glycosidases; Glycoside Hydrolases - genetics; Glycoside Hydrolases - metabolism; Glycosides; Glycosides - chemistry; Glycosides - metabolism; glycosidic linkages; Glycosylation; Herbal medicine; Humans; Hydrolysis; intestinal microorganisms; Intestine; Intestines - microbiology; Life Sciences; Medicinal plants; Medicine, Botanic; Medicine, Herbal; Microbial Genetics and Genomics; Microbiology; Mini-Review; moieties; Molecular Structure; Natural products; sugars; China; Deglycosylation; Intestinal bacteria; C–C glycosidic bond; Puerarin; C-glycosides

C-Glycosides, a special type of glycoside, are frequently distributed in many kinds of medicinal plants, such as puerarin and mangiferin, showing various and significant bioactivities. C-Glycosides are usually characterized by the C–C bond that forms between the anomeric carbon of sugar moieties and...