Accuracy assessment methods for physiological model selection toward evaluation of closed-loop controlled medical devices

• Published in: PloS one Vol. 16; no. 4; p. e0251001
• Main Authors: Bighamian, Ramin, Hahn, Jin-Oh, Kramer, George, Scully, Christopher
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 30.04.2021; Public Library of Science (PLoS)
• Subjects: Algorithms; Biology and Life Sciences; Cardiovascular system; Design and construction; Engineering and Technology; Evaluation; Feedback control systems; Medical equipment; Medicine and Health Sciences; Physical Sciences; Physiological apparatus; Research and Analysis Methods; United States

Physiological closed-loop controlled (PCLC) medical devices are complex systems integrating one or more medical devices with a patient’s physiology through closed-loop control algorithms; introducing many failure modes and parameters that impact performance. These control algorithms should be tested...