Rapamycin does not affect post-absorptive protein metabolism in human skeletal muscle - Dickinson, Jared M.; Drummond, Micah J.; Fry, Christopher S.; Gundermann, David M.; Walker, Dillon K.; Timmerman, Kyle L.; Volpi, Elena; Rasmussen, Blake B. (Metabolism, clinical and experimental, 2013)
Keywords: Absorption; Adult; Autophagy; Autophagy - drug effects; Biological and medical sciences; Biopsy; Cross-Over Studies; Endocrinology & Metabolism; Feeding. Feeding behavior; Female; FSR; Fundamental and applied biological sciences. Psychology; Humans; Immunoblotting; ingestion; Kinetics; Male; Mechanistic Target of Rapamycin Complex 1; mTOR; Multiprotein Complexes; muscle protein; Muscle Proteins - metabolism; Muscle, Skeletal - drug effects; Muscle, Skeletal - metabolism; muscles; phenylalanine; Phenylalanine - metabolism; Phosphorylation - drug effects; protein synthesis; Proteins - antagonists & inhibitors; Proteins - metabolism; Signal Transduction - drug effects; Sirolimus - pharmacology; skeletal muscle; strength training; TOR Serine-Threonine Kinases; Vertebrates: anatomy and physiology, studies on body, several organs or systems; Young Adult; RAP; CON; FSR; mTOR; 4E-BP1; LC3; mTORC1; Autophagy; Ra; S6K1; eukaryotic initiation factor 4E binding protein 1; Rapamycin trial; microtubule-associated protein 1 light chain 3; rate of appearance; fractional synthesis rate; mammalian target of rapamycin complex 1; Control trial; ribosomal S6 kinase 1; Antineoplastic agent; Human; Sirolimus; Lactone; Striated muscle; Metabolism; Macrolide; Protein; Macrocycle; Antibiotic; Protein synthesis inhibitor; Immunosuppressive agent; Endocrinology