Amygdalar neuronal plasticity and the interactions of alcohol, sex, and stress

• Published in: Brain Structure and Function Vol. 220; no. 6; pp. 3211 - 3232
• Main Authors: Retson, T. A., Hoek, J. B., Sterling, R. C., Van Bockstaele, E. J.
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.11.2015; Springer Nature B.V
• Subjects: Alcohol use; Alcoholism - metabolism; Alcoholism - pathology; Alcoholism - physiopathology; Alcoholism - psychology; Animals; Biomedical and Life Sciences; Biomedicine; Cell Biology; Central Amygdaloid Nucleus - drug effects; Central Amygdaloid Nucleus - metabolism; Central Amygdaloid Nucleus - physiology; Corticotropin-Releasing Hormone - metabolism; Disease Models, Animal; Ethanol - toxicity; Female; Male; Neurology; Neuronal Plasticity - drug effects; Neuronal Plasticity - physiology; Neurons; Neurosciences; Original Article; Proto-Oncogene Proteins c-fos - metabolism; Rats; Rats, Sprague-Dawley; Sex Factors; Sexual behavior; Stress; Stress, Physiological - physiology; c-Fos; ΔFosB; Sex differences; Chronic alcohol; Central nucleus of the amygdala

Alcohol abuse and alcoholism are major medical problems affecting both men and women. Previous animal studies reported a difference in c-Fos neuronal activation after chronic alcohol exposure; however, females remain an understudied population. To model chronic alcohol exposure match-pair fed adult...