Characterizing longitudinal white matter development during early childhood

• Published in: Brain Structure and Function Vol. 220; no. 4; pp. 1921 - 1933
• Main Authors: Dean, Douglas C., O’Muircheartaigh, Jonathan, Dirks, Holly, Waskiewicz, Nicole, Walker, Lindsay, Doernberg, Ellen, Piryatinsky, Irene, Deoni, Sean C. L.
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.07.2015; Springer Nature B.V
• Subjects: Age Factors; Biomedical and Life Sciences; Biomedicine; Brain; Brain Mapping; Cell Biology; Child; Child development; Child Development - physiology; Child, Preschool; Cognition; Female; Humans; Imaging, Three-Dimensional; Infant; Longitudinal Studies; Magnetic Resonance Imaging; Male; Neurology; Neuropsychological Tests; Neurosciences; NMR; Nuclear magnetic resonance; Original; Original Article; Sex Characteristics; White Matter - growth & development; White matter development; Myelin water fraction; Magnetic resonance imaging; Brain development

Post-mortem studies have shown the maturation of the brain’s myelinated white matter, crucial for efficient and coordinated brain communication, follows a nonlinear spatio-temporal pattern that corresponds with the onset and refinement of cognitive functions and behaviors. Unfortunately, investigati...