Gene expression profiling in subcutaneous, visceral and epigastric adipose tissues of patients with extreme obesity

• Published in: International Journal of Obesity Vol. 38; no. 3; pp. 371 - 378
• Main Authors: Gerhard, G S, Styer, A M, Strodel, W E, Roesch, S L, Yavorek, A, Carey, D J, Wood, G C, Petrick, A T, Gabrielsen, J, Ibele, A, Benotti, P, Rolston, D D, Still, C D, Argyropoulos, G
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.03.2014; Nature Publishing Group
• Subjects: 631/208/191/2018; 692/698/690/2816; 692/699/2743/393; Adipocytes; Adipose tissue; Adipose tissues; bariatric-and-metabolic-surgery-original-article; Biological and medical sciences; Biopsy; Body fat; Body mass index; Cell cycle; DNA microarrays; Epidemiology; Female; Fibroblast growth factor 1; Fibroblast Growth Factor 1 - metabolism; Fibroblast growth factor 10; Fibroblast Growth Factor 10 - metabolism; Fibroblast Growth Factor 7 - metabolism; Fibroblast growth factor receptor 7; Gastric Bypass; Gastrointestinal surgery; Gene expression; Gene Expression Profiling; Genes; Genetic aspects; Growth factors; Health Promotion and Disease Prevention; Heart surgery; Humans; Inflammation - genetics; Inflammation - pathology; Internal Medicine; Intra-Abdominal Fat - pathology; Kinases; Male; Medical sciences; Medicine; Medicine & Public Health; Metabolic Diseases; Metabolic disorders; Metabolism; Microarray Analysis; Middle Aged; Obesity; Obesity, Morbid - genetics; Obesity, Morbid - pathology; Patients; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; PPAR gamma - metabolism; Public Health; Real-Time Polymerase Chain Reaction; Severity of Illness Index; Subcutaneous Fat - pathology; Subcutaneous tissue; Transcription Factors - metabolism; Weight control; United States > US; visceral; subcutaneous adipose depot; FGF19; human epigastric; microarrays; Human; Obesity; Adipose tissue; Nutrition; Subcutaneous; Nutrition disorder; Patient; Metabolic diseases; Gene expression; Subcutaneous tissue; Nutritional status

Objective: The goal of the present study was to identify differences in gene expression between SAT, VAT and EAT depots in Class III severely obese individuals. Design: Human subcutaneous (SAT) and visceral (VAT) adipose tissues exhibit differential gene expression profiles. There is little informat...