Lung volume reduction and infection localization revealed in Big data CT imaging of COVID-19

• Published in: International journal of infectious diseases Vol. 102; pp. 316 - 318
• Main Authors: Shi, Feng, Wei, Ying, Xia, Liming, Shan, Fei, Mo, Zhanhao, Yan, Fuhua, Shen, Dinggang
• Format: Journal Article
• Language: English
• Published: Canada Elsevier Ltd 01.01.2021; The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases; Elsevier
• Subjects: Big Data; Community-Acquired Infections - diagnostic imaging; Community-Acquired Infections - physiopathology; Community-Acquired Infections - virology; Community-Acquired pneumonia; COVID-19; COVID-19 - diagnostic imaging; COVID-19 - physiopathology; COVID-19 - virology; Female; Humans; Lung; Lung - diagnostic imaging; Lung - physiopathology; Lung - virology; Male; Middle Aged; Non-Pneumonia subjects; Pandemics; Respiratory Function Tests; Retrospective Studies; SARS-CoV-2 - physiology; Short Communication; Tomography, X-Ray Computed - methods; COVID-19; Non-Pneumonia subjects; Big data; Lung; Community-Acquired pneumonia
• ISSN: 1201-9712; 1878-3511; 1878-3511
• DOI: 10.1016/j.ijid.2020.10.095

•Analysis of massive CT lung image among COVID-19, CAP, and nonpneumonia subjects.•Significantly reduced lung volume was found in COVID-19 patients.•Significantly increased lung mass and density were found in COVID-19 patients.•The infections of COVID-19 patients tend to present as bilateral lower lobes. The ongoing worldwide COVID-19 pandemic has become a huge threat to global public health. Using CT image, 3389 COVID-19 patients, 1593 community-acquired pneumonia (CAP) patients, and 1707 nonpneumonia subjects were included to explore the different patterns of lung and lung infection. We found that COVID-19 patients have a significant reduced lung volume with increased density and mass, and the infections tend to present as bilateral lower lobes. The findings provide imaging evidence to improve our understanding of COVID-19.