A Fatal Breakthrough COVID-19 Case Following Bendamustine-Rituximab Therapy

• Published in: International journal of infectious diseases Vol. 121; pp. 85 - 88
• Main Authors: Kamegai, Kohei, Iwamoto, Noriko, Togano, Tomiteru, Maeda, Kenji, Takamatsu, Yuki, Miyazato, Yusuke, Ishikane, Masahiro, Mizokami, Masashi, Sugiyama, Masaya, Iida, Shun, Miyamoto, Sho, Suzuki, Tadaki, Ohmagari, Norio
• Format: Journal Article
• Language: English
• Published: Canada Elsevier Ltd 01.08.2022; The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases; Elsevier
• Subjects: Bendamustine-rituximab therapy; Breakthrough; COVID-19; Fatal; Immune escape; COVID-19; Breakthrough; Fatal; Immune escape; Bendamustine-rituximab therapy

•We report a fatal case of breakthrough infection with the SARS-CoV-2 Delta variant after the first vaccination course.•Patients with hematologic malignancies are vulnerable to COVID-19 viral infection.•Surveillance of mixed alleles could help detect unknown aggravating factors. Although messenger r...