Subunit vaccines with a saponin-based adjuvant boost humoral and cellular immunity to MERS coronavirus - Chang, Chi-Chieh; Algaissi, Abdullah; Lai, Chia-Chun; Chang, Chun-Kai; Lin, Jr-Shiuan; Wang, Yi-Shiang; Chang, Bo-Hau; Chang, Yu-Chiuan; Chen, Wei-Ting; Fan, Yong-Qing; Peng, Bi‐Hung; Chao, Chih-Yu; et al. (Vaccine, 2023)
Keywords: Adjuvant effects; Adjuvants; Adjuvants, Immunologic; Allergy and Immunology; Amino acids; Animals; Antibodies; Antibodies, Neutralizing; Antibodies, Viral; Cell-mediated immunity; Cellular immunity; Clinical trials; Coronavirus Infections; Coronaviruses; Dipeptidyl Peptidase 4; Disease transmission; genetically modified organisms; Humans; Humoral immunity; Immunity; Immunity, Cellular; Immunization; Immunogenicity; Immunological memory; Infections; Lymphocytes; Lymphocytes T; Memory cells; MERS-CoV neutralization; Mice; Mice, Transgenic; Middle East respiratory syndrome; Middle East Respiratory Syndrome Coronavirus; mortality; Penicillin; Protein expression; Proteins; Public health; Recombinant Proteins; Respiratory diseases; Saponins; Severe acute respiratory syndrome coronavirus 2; Spike Glycoprotein, Coronavirus; Spike protein; Subunit vaccine development; subunit vaccines; T-lymphocytes; Transgenic mice; vaccination; Vaccines; Vaccines, Subunit; Viral Vaccines; Viruses; MERS-CoV neutralization; Cellular immunity; Subunit vaccine development; Adjuvant effects