Lessons from the host defences of bats, a unique viral reservoir

• Published in: Nature (London) Vol. 589; no. 7842; pp. 363 - 370
• Main Authors: Irving, Aaron T., Ahn, Matae, Goh, Geraldine, Anderson, Danielle E., Wang, Lin-Fa
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 21.01.2021; Nature Publishing Group
• Subjects: 13; 13/1; 13/106; 13/109; 13/31; 45; 45/90; 45/91; 631/181/2474; 631/250/2499; 631/326/596; 631/326/596/4130; Adaptation (Physiology); Adaptive systems; Analysis; Animals; Asymptomatic Diseases; Bats; Body size; Chiroptera; Chiroptera - immunology; Chiroptera - virology; Coronaviruses; COVID-19; Disease Reservoirs - veterinary; Disease Reservoirs - virology; Evolution; Evolution, Molecular; Host-virus relationships; Humanities and Social Sciences; Humans; Immune Tolerance; Immunological tolerance; Life span; Mammals; Middle East respiratory syndrome; multidisciplinary; Outbreaks; Pandemics; Perspective; Physiological aspects; Public health; Respiratory diseases; Science; Science (multidisciplinary); Severe acute respiratory syndrome; Tumorigenesis; Varieties; Viral diseases; Viral Zoonoses - immunology; Viral Zoonoses - transmission; Viral Zoonoses - virology; Viruses; Zoonoses; Singapore; Middle East

There have been several major outbreaks of emerging viral diseases, including Hendra, Nipah, Marburg and Ebola virus diseases, severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS)—as well as the current pandemic of coronavirus disease 2019 (COVID-19). Notably, all of...