Performance of a multiplex PCR pneumonia panel for the identification of respiratory pathogens and the main determinants of resistance from the lower respiratory tract specimens of adult patients in intensive care units

• Published in: Journal of microbiology, immunology and infection Vol. 52; no. 6; pp. 920 - 928
• Main Authors: Lee, Sze Hwei, Ruan, Sheng-Yuan, Pan, Sung-Ching, Lee, Tai-Fen, Chien, Jung-Yien, Hsueh, Po-Ren
• Format: Journal Article
• Language: English
• Published: England Elsevier B.V 01.12.2019; Taiwan Society of Microbiology. Published by Elsevier Taiwan LLC; Elsevier
• Subjects: Adult; Aged; Aged, 80 and over; Bacteria - genetics; Bacteria - isolation & purification; Bronchoalveolar Lavage Fluid - microbiology; Female; FilmArray pneumonia panel; Humans; Intensive Care Units - statistics & numerical data; Male; Middle Aged; Multiplex Polymerase Chain Reaction; Oligonucleotide Array Sequence Analysis; Original; Pathogen detection; Pneumonia; Pneumonia - diagnosis; Pneumonia - microbiology; Pneumonia - virology; Resistant genes; Respiratory failure; Respiratory Tract Infections - diagnosis; Respiratory Tract Infections - microbiology; Respiratory Tract Infections - virology; Sputum - microbiology; Sputum - virology; Viruses - genetics; Viruses - isolation & purification; Pathogen detection; Pneumonia; Respiratory failure; Performance; Resistant genes; FilmArray pneumonia panel

Timely diagnostic investigation to establish the microbial etiology of pneumonia is essential to ensure the administration of effective antibiotic therapy to individual patients. We evaluated a multiplex PCR assay panel, the FilmArray® pneumonia panel (FilmArray PP, BioFire Diagnostics), for detecti...