The support of human genetic evidence for approved drug indications - Nelson, Matthew R; Tipney, Hannah; Painter, Jeffery L; Shen, Judong; Nicoletti, Paola; Shen, Yufeng; Floratos, Aris; Sham, Pak Chung; Li, Mulin Jun; Wang, Junwen; Cardon, Lon R; Whittaker, John C; et al. (Nature genetics, 2015)
Keywords: 631/154/1435; 631/208/205; Agriculture; analysis; Animal Genetics and Genomics; Biomedicine; Cancer Research; Chromosome Mapping; Databases, Genetic - statistics & numerical data; Drug Approval - statistics & numerical data; Drug interactions; Drug metabolism; Drugs; Gene Function; Genes; Genetic aspects; Genetic Association Studies - statistics & numerical data; Genetic Predisposition to Disease - genetics; Genetic research; Genetics; Genetics, Medical - methods; Genetics, Medical - statistics & numerical data; Genome-Wide Association Study - statistics & numerical data; Human Genetics; Humans; Innovations; Linkage Disequilibrium; Medical Subject Headings - utilization; Molecular targeted therapy; Molecular Targeted Therapy - statistics & numerical data; Pharmacology; Polymorphism, Single Nucleotide