A genome-wide association study in the Japanese population identifies the 12q24 locus for habitual coffee consumption: The J-MICC Study

• Published in: Scientific reports Vol. 8; no. 1; pp. 1493 - 11
• Main Authors: Nakagawa-Senda, Hiroko, Hachiya, Tsuyoshi, Shimizu, Atsushi, Hosono, Satoyo, Oze, Isao, Watanabe, Miki, Matsuo, Keitaro, Ito, Hidemi, Hara, Megumi, Nishida, Yuichiro, Endoh, Kaori, Kuriki, Kiyonori, Katsuura-Kamano, Sakurako, Arisawa, Kokichi, Nindita, Yora, Ibusuki, Rie, Suzuki, Sadao, Hosono, Akihiro, Mikami, Haruo, Nakamura, Yohko, Takashima, Naoyuki, Nakamura, Yasuyuki, Kuriyama, Nagato, Ozaki, Etsuko, Furusyo, Norihiro, Ikezaki, Hiroaki, Nakatochi, Masahiro, Sasakabe, Tae, Kawai, Sayo, Okada, Rieko, Hishida, Asahi, Naito, Mariko, Wakai, Kenji, Momozawa, Yukihide, Kubo, Michiaki, Tanaka, Hideo
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 24.01.2018; Nature Publishing Group
• Subjects: 38/22; 45/23; 45/43; 631/208/205/2138; 631/67/2324; Asian Continental Ancestry Group - genetics; Beverages; Chromosome 12; Chromosomes, Human, Pair 12 - genetics; Coffee; Coffee - adverse effects; Cohort Studies; Female; Gene Expression Regulation - drug effects; Genetic diversity; Genetic variance; Genome-wide association studies; Genome-Wide Association Study; Genomes; Health risk assessment; Humanities and Social Sciences; Humans; Male; Middle Aged; multidisciplinary; Polymorphism, Single Nucleotide; Population; Population studies; Replication; Risk Factors; Science; Science (multidisciplinary); Surveys and Questionnaires

Coffee is one of the most widely consumed beverages worldwide, and its role in human health has received much attention. Although genome-wide association studies (GWASs) have investigated genetic variants associated with coffee consumption in European populations, no such study has yet been conducte...