KDM4A regulates the maternal-to-zygotic transition by protecting broad H3K4me3 domains from H3K9me3 invasion in oocytes - Sankar, Aditya; Lerdrup, Mads; Manaf, Adeel; Johansen, Jens Vilstrup; Gonzalez, Javier Martin; Borup, Rehannah; Blanshard, Robert; Klungland, Arne; Hansen, Klaus; Andersen, Claus Yding; Dahl, John Arne; Helin, Kristian; et al. (Nature cell biology, 2020)
Keywords: 14/1; 14/19; 14/34; 38/1; 38/91; 45/15; 45/91; 631/136/2086; 631/337/176; 64/110; Animals; Biomedical and Life Sciences; Cancer Research; Catalytic activity; Cell Biology; Demethylation; Developmental Biology; Domains; Embryo Implantation; Embryo, Mammalian; Embryonic development; Embryos; Enzymes; Epigenetic inheritance; Epigenetics; Female; Fertilization; Fertilization - genetics; Gametocytes; Genetic aspects; Genetic research; Genomes; Heterochromatin; Heterochromatin - chemistry; Heterochromatin - metabolism; Histone Demethylases - genetics; Histone Demethylases - metabolism; Histone H3; Histones; Histones - genetics; Histones - metabolism; Hydrolases; Implantation; Letter; Life Sciences; Lysine; Male; Mammals; Metaphase; Methylation; Mice; Mice, Knockout; Oocytes; Oocytes - cytology; Oocytes - growth & development; Oocytes - metabolism; Post-translation; Post-translational modification; Priming; Promoter Regions, Genetic; Protein Processing, Post-Translational; Stem Cells; Transcription activation; Transcription, Genetic; Zygote - cytology; Zygote - growth & development; Zygote - metabolism; Zygotes; Denmark