Heroin vaccine: Using titer, affinity, and antinociception as metrics when examining sex and strain differences - Hwang, Candy S.; Smith, Lauren C.; Wenthur, Cody J.; Ellis, Beverly; Zhou, Bin; Janda, Kim D. (Vaccine, 2019)
Keywords: Allergy and Immunology; Binding sites; Conjugate vaccine; cytokines; Drug abuse; Experiments; Females; Gender differences; genetic variation; Heroin; human population; Human populations; Hypersensitivity; Immune response; Immune system; Immunization; Immunoglobulin E; Inbreeding; Laboratory animals; Males; mice; Mouse; Narcotics; Pain perception; Quarantine; Sex; Sex differences; Sexes; Strain; strain differences; Substance use; Tetanus; vaccination; Vaccines; Women; United States--US; PBS; TT; SUD; SW; Conjugate vaccine; Sex differences; s.c; i.p; CpG ODN; Strain; BSA; Mouse; SPR; NHS; J:DO; 6-AM; Heroin; Jackson Diversity:Outbred; N-hydroxysuccinimide; subcutaneous; CpG oligodeoxynucleotides; surface plasmon resonance; Swiss Webster; 6-acetylmorphine; tetanus toxoid; intraperitoneal; substance use disorder; phosphate buffered saline; bovine serum albumin