598-P: Sex-Specific Differences of Human Skeletal Muscle—A Multiomics Exercise Study

• Published in: Diabetes (New York, N.Y.) Vol. 73; no. Supplement_1; p. 1
• Main Authors: DREHER, SIMON I., GOJ, THOMAS, VON TOERNE, CHRISTINE, HOENE, MIRIAM, IRMLER, MARTIN, OUNI, MERIEM, JÄHNERT, MARKUS, BECKERS, JOHANNES, PETER, ANDREAS, BIRKENFELD, ANDREAS L., SCHÜRMANN, ANNETTE, HAUCK, STEFANIE M., WEIGERT, CORA
• Format: Journal Article
• Language: English
• Published: New York American Diabetes Association 14.06.2024
• Subjects: Aerobic capacity; Biopsy; CpG islands; Diabetes mellitus (non-insulin dependent); DNA methylation; Exercise; Gene regulation; Glycolysis; Histones; Homeostasis; Males; Musculoskeletal system; Myoblasts; Myotubes; Oxidative stress; Proteins; Proteomics; Sex; Skeletal muscle; Transcriptomics

Exercise is a potent skeletal muscle stimulus and one of the most effective strategies to prevent muscle loss and type 2 diabetes. Biological sex-based differences are reported for aerobic capacity, muscle mass, and exercise performance. We aimed to provide a yet missing comprehensive picture of mol...