Daphnetin inhibits proliferation and inflammatory response in human HaCaT keratinocytes and ameliorates imiquimod-induced psoriasis-like skin lesion in mice - Gao, Jintao; Chen, Fangru; Fang, Huanan; Mi, Jing; Qi, Qi; Yang, Mengjuan (Biological research, 2020)
Keywords: Adjuvants, Immunologic - adverse effects; Analysis; Animals; Anti-Inflammatory Agents - pharmacology; Antiviral drugs; Apoptosis; BIOLOGY; Cell growth; Cell Proliferation; Cell viability; Cholecystokinin; Cytokines; Daphnetin; Dermatologic agents; Dermatology; Erythema; Formulae, receipts, prescriptions; Humans; IL-1β; Imiquimod; Imiquimod - adverse effects; Immunofluorescence; Inflammation; Inflammation - drug therapy; Inflammatory response; Interleukin 22; Interleukin 6; Interleukin 8; Keratin; Keratinocytes; Mice; Mice, Inbred BALB C; Monocyte chemoattractant protein 1; mRNA; NF-κB protein; NF-κb signaling pathway; Nuclear nonproliferation; Nuclear transport; Oncostatin M; Pathogenesis; Phosphorylation; Proliferation; Psoriasis; Psoriasis - chemically induced; Psoriasis - drug therapy; Rabbits; RNA; Signal transduction; Skin; Skin diseases; Skin lesions; Tumor necrosis factor; Tumor necrosis factor-α; Umbelliferones - pharmacology; Western blotting; Inflammatory response; Daphnetin; NF-κb signaling pathway; Proliferation; Psoriasis