A double-blind, placebo-controlled, cross-over study to establish the bifidogenic effect of a very-long-chain inulin extracted from globe artichoke (Cynara scolymus) in healthy human subjects

• Published in: British journal of nutrition Vol. 104; no. 7; pp. 1007 - 1017
• Main Authors: Costabile, Adele, Kolida, Sofia, Klinder, Annett, Gietl, Eva, Bäuerlein, Michael, Frohberg, Claus, Landschütze, Volker, Gibson, Glenn R.
• Format: Journal Article
• Language: English
• Published: Cambridge, UK Cambridge University Press 14.10.2010
• Subjects: Adult; adults; Bifidobacterium - drug effects; Bifidobacterium - growth & development; Bifidogenic effect; Biological and medical sciences; Colon - microbiology; Cross-Over Studies; cross-sectional studies; Cynara cardunculus; Cynara scolymus; Cynara scolymus - chemistry; Dietary fiber; Dietary Fiber - administration & dosage; Digestive system; Double-Blind Method; feces; Feces - chemistry; Feeding. Feeding behavior; Female; Fundamental and applied biological sciences. Psychology; Gas production; Gases; Humans; Inflorescence; Ingestion; Intestinal microflora; intestinal microorganisms; Inulin - adverse effects; Inulin - pharmacology; Lactobacillus; Lactobacillus - drug effects; Lactobacillus - growth & development; Male; maltodextrins; Microbiology; Oil and gas production; Plant Extracts - adverse effects; Plant Extracts - pharmacology; Polysaccharides; Prebiotics; Probiotics; Reference Values; Vertebrates: anatomy and physiology, studies on body, several organs or systems; very-long-chain inulin; Young Adult; Gas production; Bifidogenic effect; Intestinal microflora; Prebiotics; Human; Healthy subject; Digestive system; Long chain; Gut; Microflora; Extract; Vertebrata; Mammalia; Inulin; Double blind study; Prebiotic

There is growing interest in the use of inulins as substrates for the selective growth of beneficial gut bacteria such as bifidobacteria and lactobacilli because recent studies have established that their prebiotic effect is linked to several health benefits. In the present study, the impact of a ve...