A computationally designed ACE2 decoy has broad efficacy against SARS-CoV-2 omicron variants and related viruses in vitro and in vivo - Havranek, Brandon; Lindsey, Graeme Walker; Higuchi, Yusuke; Itoh, Yumi; Suzuki, Tatsuya; Okamoto, Toru; Hoshino, Atsushi; Procko, Erik; Islam, Shahidul M. (Communications Biology, 2023)
Keywords: 631/114/469; 631/154/51/2314; 631/57/2266; 82; 82/80; 82/81; 82/83; 96; 96/31; ACE2; Affinity; Angiotensin-converting enzyme 2; Angiotensin-Converting Enzyme 2 - genetics; Angiotensin-Converting Enzyme 2 - therapeutic use; antibodies; Antibodies, Monoclonal; Biology; Biology (General); Biomedical and Life Sciences; Computer applications; COVID-19; Design; Humans; Life Sciences; Medical Biochemistry; Medical Sciences; Medicine and Health Sciences; monoclonal; Monoclonal antibodies; Protein Engineering; QH301-705.5; SARS-CoV-2; SARS-CoV-2 - genetics; Severe acute respiratory syndrome coronavirus 2; Vaccination