556-P: Noninvasive Measurements of AGE Products in the Crystalline Lens of the Eye Can Distinguish Subjects with Prediabetes and Type 2 Diabetes and Correlated with Severity of Neuropathy

• Published in: Diabetes (New York, N.Y.) Vol. 68; no. Supplement_1
• Main Author: TAVAKOLI, MITRA
• Format: Journal Article
• Language: English
• Published: New York American Diabetes Association 01.06.2019
• Subjects: Advanced glycosylation end products; Confocal microscopy; Cornea; Diabetes; Diabetes mellitus; Diabetes mellitus (non-insulin dependent); Diabetic neuropathy; Eye lens; Glucose tolerance; Glycosylation; Morphology; Nerves; Patients; Retinopathy

The accumulation of advanced glycation end products (AGEs) in the body contributes to pathogenesis of many diseases including complications of diabetes including retinopathy and neuropathy. Proteins in the lens of the eye do not turnover and therefore give an indication of the average glucose levels...