Constitutive Expression of Adiponectin in Endothelial Progenitor Cells Protects a Rat Model of Cerebral Ischemia

• Published in: Journal of neural transplantation & plasticity Vol. 2017; no. 2017; pp. 1 - 8
• Main Authors: Liu, Yumin, Wang, Meiyao, Feng, Hongliang, Yu, Qing, Xie, Xiaorui, Zhang, Renwei, Li, Yan
• Format: Journal Article
• Language: English
• Published: Cairo, Egypt Hindawi Publishing Corporation 01.01.2017; Hindawi; John Wiley & Sons, Inc; Wiley
• Subjects: Antibodies; Bone marrow; Carotid arteries; Cerebral ischemia; Endothelium; Experiments; Ischemia; Laboratory animals; Peptide hormones; Physiological aspects; Proteins; Stroke; Veins & arteries; China

Endothelial progenitor cells (EPCs), as precursors to endothelial cells, play a significant part in the process of endogenous blood vessel repair and maintenance of endothelial integrity. Adiponectin (APN) is an adipocyte-specific adipocytokine. In this study, we aim to test whether we transplant a...