Gastrointestinal Symptoms in 2- to 5-Year-Old Children in the Study to Explore Early Development
Gastrointestinal symptoms (GIS) are commonly reported in children with autism spectrum disorder (ASD). This multi-site study evaluated the prevalence of GIS in preschool-aged children with ASD/(n = 672), with other developmental delays (DD)/(n = 938), and children in the general population (POP)/(n ...
Saved in:
| Published in | Journal of autism and developmental disorders Vol. 51; no. 11; pp. 3806 - 3817 |
|---|---|
| Main Authors | , , , , , , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
New York
Springer US
01.11.2021
Springer Springer Nature B.V |
| Subjects | |
| Online Access | Get full text |
Cover
Loading…
| Abstract | Gastrointestinal symptoms (GIS) are commonly reported in children with autism spectrum disorder (ASD). This multi-site study evaluated the prevalence of GIS in preschool-aged children with ASD/(n = 672), with other developmental delays (DD)/(n = 938), and children in the general population (POP)/(n = 851). After adjusting for covariates, children in the ASD group were over 3 times more likely to have parent-reported GIS than the POP group, and almost 2 times more likely than the DD group. Children with GIS from all groups had more behavioral and sleep problems. Within the ASD group, children with developmental regression had more GIS than those without; however, there were no differences in autism severity scores between children with and without GIS. These findings have implications for clinical management. |
|---|---|
| AbstractList | Gastrointestinal symptoms (GIS) are commonly reported in children with autism spectrum disorder (ASD). This multi-site study evaluated the prevalence of GIS in preschool-aged children with ASD/(n = 672), with other developmental delays (DD)/(n = 938), and children in the general population (POP)/(n = 851). After adjusting for covariates, children in the ASD group were over 3 times more likely to have parent-reported GIS than the POP group, and almost 2 times more likely than the DD group. Children with GIS from all groups had more behavioral and sleep problems. Within the ASD group, children with developmental regression had more GIS than those without; however, there were no differences in autism severity scores between children with and without GIS. These findings have implications for clinical management. Gastrointestinal symptoms (GIS) are commonly reported in children with autism spectrum disorder (ASD). This multi-site study evaluated the prevalence of GIS in preschool-aged children with ASD/(n = 672), with other developmental delays (DD)/(n = 938), and children in the general population (POP)/(n = 851). After adjusting for covariates, children in the ASD group were over 3 times more likely to have parent-reported GIS than the POP group, and almost 2 times more likely than the DD group. Children with GIS from all groups had more behavioral and sleep problems. Within the ASD group, children with developmental regression had more GIS than those without; however, there were no differences in autism severity scores between children with and without GIS. These findings have implications for clinical management.Gastrointestinal symptoms (GIS) are commonly reported in children with autism spectrum disorder (ASD). This multi-site study evaluated the prevalence of GIS in preschool-aged children with ASD/(n = 672), with other developmental delays (DD)/(n = 938), and children in the general population (POP)/(n = 851). After adjusting for covariates, children in the ASD group were over 3 times more likely to have parent-reported GIS than the POP group, and almost 2 times more likely than the DD group. Children with GIS from all groups had more behavioral and sleep problems. Within the ASD group, children with developmental regression had more GIS than those without; however, there were no differences in autism severity scores between children with and without GIS. These findings have implications for clinical management. |
| Audience | Academic |
| Author | Croen, Lisa A. Reynolds, Ann M. Soke, Gnakub N. Levy, Susan E. Wiggins, Lisa Daniels, Julie L. Pinto-Martin, Jennifer A. Fallin, M. Daniele Lee, Li- Ching Kral, Tanja V. E. Sims, Amy Schieve, Laura A. Newschaffer, Craig J. Sabourin, Katherine R. |
| AuthorAffiliation | 3 Kaiser Permanent, 3600 Broadway, Oakland, CA 94611, USA 5 Johns Hopkins Bloomberg School of Public Health, 624 N. Broadway, Baltimore, MD HH85021205, USA 10 Present Address: Polio Eradication Branch at the Centers for Disease Control and Prevention, Center for Global Health, Global Immunization Division, 1600 Clifton Rd, Atlanta, NE 30333, USA 6 University of Pennsylvania, 418 Curie Boulevard, Philadelphia, PA 19104, USA 8 The Children’s Hospital of Philadelphia, 2716 South Street, Philadelphia, PA 19146, USA 1 University of Colorado, School of Medicine, 13123 East 16th Ave, B-140, Aurora, CO 80045, USA 7 Michigan State University, 909 Wilson Road, East Lansing, MI B50048824, USA 2 National Center On Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, 4770 Buford Highway, Chamblee, GA S106-330341, USA 9 Present Address: The Pennsylvania State University, College of Health and Human Development, 325 Health and Human Development Building, University Park, |
| AuthorAffiliation_xml | – name: 6 University of Pennsylvania, 418 Curie Boulevard, Philadelphia, PA 19104, USA – name: 4 University of North Carolina at Chapel Hill, Campus Box 7435, Chapel Hill, NC 27599, USA – name: 8 The Children’s Hospital of Philadelphia, 2716 South Street, Philadelphia, PA 19146, USA – name: 2 National Center On Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, 4770 Buford Highway, Chamblee, GA S106-330341, USA – name: 3 Kaiser Permanent, 3600 Broadway, Oakland, CA 94611, USA – name: 9 Present Address: The Pennsylvania State University, College of Health and Human Development, 325 Health and Human Development Building, University Park, PA 16802, USA – name: 7 Michigan State University, 909 Wilson Road, East Lansing, MI B50048824, USA – name: 1 University of Colorado, School of Medicine, 13123 East 16th Ave, B-140, Aurora, CO 80045, USA – name: 5 Johns Hopkins Bloomberg School of Public Health, 624 N. Broadway, Baltimore, MD HH85021205, USA – name: 10 Present Address: Polio Eradication Branch at the Centers for Disease Control and Prevention, Center for Global Health, Global Immunization Division, 1600 Clifton Rd, Atlanta, NE 30333, USA |
| Author_xml | – sequence: 1 givenname: Ann M. orcidid: 0000-0002-0836-746X surname: Reynolds fullname: Reynolds, Ann M. email: ann.reynolds@childrenscolorado.org organization: University of Colorado, School of Medicine – sequence: 2 givenname: Gnakub N. surname: Soke fullname: Soke, Gnakub N. organization: National Center On Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Polio Eradication Branch at the Centers for Disease Control and Prevention, Center for Global Health, Global Immunization Division – sequence: 3 givenname: Katherine R. surname: Sabourin fullname: Sabourin, Katherine R. organization: University of Colorado, School of Medicine – sequence: 4 givenname: Lisa A. surname: Croen fullname: Croen, Lisa A. organization: Kaiser Permanent – sequence: 5 givenname: Julie L. surname: Daniels fullname: Daniels, Julie L. organization: University of North Carolina at Chapel Hill – sequence: 6 givenname: M. Daniele surname: Fallin fullname: Fallin, M. Daniele organization: Johns Hopkins Bloomberg School of Public Health – sequence: 7 givenname: Tanja V. E. surname: Kral fullname: Kral, Tanja V. E. organization: University of Pennsylvania – sequence: 8 givenname: Li- Ching surname: Lee fullname: Lee, Li- Ching organization: Johns Hopkins Bloomberg School of Public Health – sequence: 9 givenname: Craig J. surname: Newschaffer fullname: Newschaffer, Craig J. organization: Johns Hopkins Bloomberg School of Public Health, The Pennsylvania State University, College of Health and Human Development – sequence: 10 givenname: Jennifer A. surname: Pinto-Martin fullname: Pinto-Martin, Jennifer A. organization: University of Pennsylvania – sequence: 11 givenname: Laura A. surname: Schieve fullname: Schieve, Laura A. organization: National Center On Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention – sequence: 12 givenname: Amy surname: Sims fullname: Sims, Amy organization: Michigan State University – sequence: 13 givenname: Lisa surname: Wiggins fullname: Wiggins, Lisa organization: National Center On Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention – sequence: 14 givenname: Susan E. surname: Levy fullname: Levy, Susan E. organization: The Children’s Hospital of Philadelphia |
| BackLink | http://eric.ed.gov/ERICWebPortal/detail?accno=EJ1312783$$DView record in ERIC https://www.ncbi.nlm.nih.gov/pubmed/33394243$$D View this record in MEDLINE/PubMed |
| BookMark | eNp9kl9v0zAUxS00xLrCF0ACReIFHjz8J4mdl0lTKWNo0iQKDzwZ13FaT45dbGdavz0uHR2dqikPkXJ-597onnMCjpx3GoDXGJ1ihNjHiBFHFCKCICoZr2HzDIxwxSikJSVHYIRwTSAlFTsGJzHeIIQaTsgLcEwpbUpS0hH4dSFjCt64pGMyTtpitu5XyfexMK4gsEi-qOBPLQO8tm0xWRrbBu02YlrqYpaGdr1hpncr64MupjLYdfFJ32rrV7126SV43kkb9av79xj8-Dz9PvkCr64vLifnV1DVtEpQs7bBFCMqJUedVGROOlJ3iJK6nVPFte4IV4R1kpQ1Vk3JO9kRWTZKlbQtCR2Ds-3c1TDvdavy6iCtWAXTy7AWXhqxrzizFAt_KzhlFWE4D3h_PyD430O-huhNVNpa6bQfoiAlq1BTccQz-u4ReuOHkI-XqYrjHE5TswdqIa0WxnU-71WboeK8ZpwzjHNOYwAPUAvtdP7JnHdn8uc9_vQAn59W90YdNHzYM2Qm6bu0kEOM4nL2bZ99-_8Rd9f715cMvNkCOhi1k6dfc3SE8Y1OtroKPsagux2DkdiUVmxLK3Jpxd_Siiab-COTMkkm4zdBGfu0lW6tMe9xCx0eknjC9QedBfxL |
| CitedBy_id | crossref_primary_10_3389_fped_2023_1120728 crossref_primary_10_3390_ijms241814042 crossref_primary_10_1007_s10803_024_06387_2 crossref_primary_10_1016_j_dhjo_2020_101052 crossref_primary_10_9758_cpn_24_1179 crossref_primary_10_3389_fpsyt_2022_963102 crossref_primary_10_1002_ajmg_b_32952 crossref_primary_10_3390_nu14071471 |
| Cites_doi | 10.1542/peds.2013-3995 10.1016/j.pediatrneurol.2008.07.019 10.1093/sleep/23.8.1d 10.1001/jamapsychiatry.2014.3034 10.1002/aur.1646 10.1007/s10803-012-1461-8 10.1002/aur.1238 10.1542/peds.2012-0900L 10.1002/ajmg.b.32567 10.1542/peds.2008-0819 10.1038/nn.4476 10.1007/BF02172145 10.1037/t17256-000 10.1542/peds.2013-0819 10.1111/j.1440-1754.2011.02251.x 10.1001/archpedi.154.6.549 10.1097/DBP.0b013e31821bd06a 10.1097/MPG.0000000000001174 10.3109/00365529709011203 10.1542/peds.2009-1878C 10.1002/aur.237 10.1007/s10803-013-1973-x 10.1007/s10802-012-9668-x 10.1016/j.jpeds.2012.11.082 10.1007/s10803-014-2287-3 10.1542/peds.2018-0492 10.1002/aur.1492 |
| ContentType | Journal Article |
| Copyright | Springer Science+Business Media, LLC, part of Springer Nature 2021 2021. Springer Science+Business Media, LLC, part of Springer Nature. COPYRIGHT 2021 Springer Springer Science+Business Media, LLC, part of Springer Nature 2021. |
| Copyright_xml | – notice: Springer Science+Business Media, LLC, part of Springer Nature 2021 – notice: 2021. Springer Science+Business Media, LLC, part of Springer Nature. – notice: COPYRIGHT 2021 Springer – notice: Springer Science+Business Media, LLC, part of Springer Nature 2021. |
| DBID | AAYXX CITATION 7SW BJH BNH BNI BNJ BNO ERI PET REK WWN CGR CUY CVF ECM EIF NPM ISR 0-V 3V. 7QJ 7RV 7TK 7X7 7XB 88B 88E 88G 88J 8A4 8FI 8FJ 8FK 8G5 ABUWG AFKRA AHOVV ALSLI AZQEC BENPR CCPQU CJNVE DWQXO FYUFA GHDGH GNUQQ GUQSH HEHIP K9- K9. KB0 M0P M0R M0S M1P M2M M2O M2R M2S MBDVC NAPCQ PHGZM PHGZT PJZUB PKEHL POGQB PPXIY PQEDU PQEST PQQKQ PQUKI PRINS PRQQA PSYQQ Q9U 7X8 5PM |
| DOI | 10.1007/s10803-020-04786-9 |
| DatabaseName | CrossRef ERIC ERIC (Ovid) ERIC ERIC ERIC (Legacy Platform) ERIC( SilverPlatter ) ERIC ERIC PlusText (Legacy Platform) Education Resources Information Center (ERIC) ERIC Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed Gale In Context: Science ProQuest Social Sciences Premium Collection ProQuest Central (Corporate) Applied Social Sciences Index & Abstracts (ASSIA) Nursing & Allied Health Database Neurosciences Abstracts Health & Medical Collection ProQuest Central (purchase pre-March 2016) Education Database (Alumni Edition) Medical Database (Alumni Edition) Psychology Database (Alumni) Social Science Database (Alumni Edition) Education Periodicals Hospital Premium Collection Hospital Premium Collection (Alumni Edition) ProQuest Central (Alumni) (purchase pre-March 2016) ProQuest Research Library ProQuest Central (Alumni) ProQuest Central UK/Ireland Education Research Index Social Science Premium Collection ProQuest Central Essentials ProQuest Central ProQuest One Community College Education Collection ProQuest Central Korea Health Research Premium Collection Health Research Premium Collection (Alumni) ProQuest Central Student ProQuest Research Library Sociology Collection Consumer Health Database (Alumni Edition) ProQuest Health & Medical Complete (Alumni) Nursing & Allied Health Database (Alumni Edition) Education Database Consumer Health Database ProQuest Health & Medical Collection Medical Database ProQuest Psychology Database Research Library Social Science Database Sociology Database Research Library (Corporate) Nursing & Allied Health Premium ProQuest Central Premium ProQuest One Academic (New) ProQuest Health & Medical Research Collection ProQuest One Academic Middle East (New) ProQuest Sociology & Social Sciences Collection ProQuest One Health & Nursing ProQuest One Education ProQuest One Academic Eastern Edition (DO NOT USE) ProQuest One Academic ProQuest One Academic UKI Edition ProQuest Central China ProQuest One Social Sciences ProQuest One Psychology ProQuest Central Basic MEDLINE - Academic PubMed Central (Full Participant titles) |
| DatabaseTitle | CrossRef ERIC MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) ProQuest One Education ProQuest One Psychology Research Library Prep ProQuest Central Student ProQuest Central Essentials Sociology & Social Sciences Collection ProQuest Central China Health Research Premium Collection Health & Medical Research Collection ProQuest Central (New) ProQuest Sociology ProQuest Medical Library (Alumni) Social Science Premium Collection Education Collection ProQuest Family Health ProQuest One Academic Eastern Edition ProQuest Hospital Collection Sociology Collection Health Research Premium Collection (Alumni) ProQuest Professional Education Neurosciences Abstracts ProQuest Hospital Collection (Alumni) Nursing & Allied Health Premium ProQuest Health & Medical Complete ProQuest Social Science Journals ProQuest Social Sciences Premium Collection ProQuest One Academic UKI Edition ProQuest Nursing & Allied Health Source (Alumni) ProQuest One Academic ProQuest One Academic (New) ProQuest Sociology & Social Sciences Collection ProQuest One Academic Middle East (New) ProQuest Social Science Journals (Alumni Edition) ProQuest Health & Medical Complete (Alumni) ProQuest Central (Alumni Edition) ProQuest One Community College ProQuest One Health & Nursing Research Library (Alumni Edition) ProQuest Family Health (Alumni Edition) Applied Social Sciences Index and Abstracts (ASSIA) ProQuest Central ProQuest Health & Medical Research Collection Health and Medicine Complete (Alumni Edition) ProQuest Central Korea ProQuest Research Library ProQuest Sociology Collection ProQuest One Social Sciences ProQuest Central Basic ProQuest Education Journals ProQuest Nursing & Allied Health Source ProQuest Psychology Journals (Alumni) ProQuest Medical Library ProQuest Psychology Journals ProQuest Education Journals (Alumni Edition) ProQuest Central (Alumni) MEDLINE - Academic |
| DatabaseTitleList | ERIC MEDLINE - Academic MEDLINE ProQuest One Education |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database – sequence: 3 dbid: ERI name: ERIC url: https://eric.ed.gov/ sourceTypes: Index Database – sequence: 4 dbid: BENPR name: ProQuest Central url: https://www.proquest.com/central sourceTypes: Aggregation Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine Public Health Education Psychology |
| EISSN | 1573-3432 |
| ERIC | EJ1312783 |
| EndPage | 3817 |
| ExternalDocumentID | PMC8375271 A678871134 33394243 EJ1312783 10_1007_s10803_020_04786_9 |
| Genre | Multicenter Study Journal Article |
| GeographicLocations | United States |
| GeographicLocations_xml | – name: United States |
| GrantInformation_xml | – fundername: National Center on Birth Defects and Developmental Disabilities grantid: 01086, 02199, DD11-002, DD06-003, DD04-001, and DD09-002 funderid: http://dx.doi.org/10.13039/100006087 – fundername: National Center for Advancing Translational Sciences grantid: UL1TR001082 funderid: http://dx.doi.org/10.13039/100006108 – fundername: NCBDD CDC HHS grantid: 01086, 02199, DD11-002, DD06-003, DD04-001, and DD09-002 – fundername: NCBDD CDC HHS grantid: U01 DD001210 – fundername: NCATS NIH HHS grantid: UL1 TR001082 – fundername: Intramural CDC HHS grantid: CC999999 – fundername: NCATS NIH HHS grantid: UL1TR001082 |
| GroupedDBID | --- -4V -55 -5G -BR -EM -W8 -XW -XX -Y2 -~C -~X ..I .86 .GJ .GO .VR 0-V 04C 06D 07C 0R~ 0VY 199 1N0 1VV 2.D 203 28- 29J 2J2 2JN 2JY 2KG 2KM 2LR 2P1 2VQ 2~H 30V 36B 3V. 4.4 406 408 409 40D 40E 53G 5GY 5QI 5VS 67Z 6NX 6PF 78A 7RV 7X7 85S 88E 8A4 8FI 8FJ 8G5 8TC 8UJ 95- 95. 95~ 96X 9M8 AABHQ AACDK AAHNG AAHSB AAIAL AAJBT AAJKR AANZL AARHV AARTL AASML AATNV AATVU AAUTI AAUYE AAWCG AAWTL AAYIU AAYJJ AAYQN AAYTO AAYZH ABAKF ABBBX ABBXA ABDBF ABDZT ABECU ABFTV ABHLI ABHQN ABIPD ABIVO ABJNI ABJOX ABKCH ABKTR ABMNI ABMQK ABNWP ABPLI ABQBU ABQSL ABSXP ABTAH ABTEG ABTHY ABTKH ABTMW ABULA ABUWG ABUWZ ABWNU ABXPI ACAOD ACBXY ACDTI ACGFS ACHQT ACHSB ACHXU ACIHN ACIPQ ACKNC ACMDZ ACMLO ACNCT ACOKC ACOMO ACPIV ACPRK ACPVT ACTDY ACUHS ACYUM ACZOJ ADBBV ADHHG ADHIR ADINQ ADJJI ADKNI ADKPE ADOJX ADRFC ADTPH ADURQ ADYFF ADZKW AEAQA AEBTG AEFIE AEFQL AEGAL AEGNC AEJHL AEJRE AEKMD AEMSY AEOHA AEPYU AESKC AETLH AEVLU AEXYK AFBBN AFEXP AFFNX AFGCZ AFKRA AFLOW AFQWF AFWTZ AFZKB AGAYW AGDGC AGGDS AGJBK AGMZJ AGQEE AGQMX AGRTI AGWIL AGWZB AGYKE AHAVH AHBYD AHIZS AHKAY AHMBA AHSBF AHYZX AI. AIAKS AIGIU AIIXL AIKWM AILAN AITGF AJBLW AJRNO AJZVZ ALIPV ALMA_UNASSIGNED_HOLDINGS ALSLI ALWAN AMKLP AMXSW AMYLF AMYQR AOCGG ARALO ARMRJ ASOEW AXYYD AYQZM AZFZN AZQEC B-. B0M BA0 BBWZM BDATZ BENPR BGNMA BKEYQ BKNYI BMSDO BPHCQ BSONS BVXVI CAG CCPQU CJNVE COF CS3 CSCUP DDRTE DL5 DNIVK DPUIP DU5 DWQXO EAD EAP EBD EBLON EBS ECF ECT ECV EDJ EHN EIHBH EIOEI EJD EMB EMK EMOBN ENC EPL EPS EPT ESBYG ESX EX3 F5P FEDTE FERAY FFXSO FIGPU FINBP FNLPD FRRFC FSGXE FWDCC FYUFA GGCAI GGRSB GJIRD GNUQQ GNWQR GQ6 GQ7 GQ8 GUQSH GXS H13 HEHIP HF~ HG5 HG6 HMCUK HMJXF HQYDN HRMNR HVGLF HZ~ H~9 I09 IAO IEA IER IHE IHR IJ- IKXTQ IMOTQ INH INR IOF IPY IRVIT ISR ITC ITM IWAJR IXC IZIGR IZQ I~X I~Z J-C J0Z JBSCW JCJTX JZLTJ K9- KDC KOV KOW L7B LAK LLZTM LPU M0P M0R M1P M2M M2O M2R M2S M4Y MA- MVM N2Q NAPCQ NB0 NDZJH NHB NPVJJ NQJWS NU0 O-J O9- O93 O9G O9I O9J OAM OHT OVD P19 P2P P9L PCD PF- PQEDU PQQKQ PROAC PSQYO PSYQQ PT4 PT5 Q2X QF4 QM7 QN7 QOK QOS Q~Q R-Y R4E R89 R9I RHV RNI ROL RPX RRX RSV RZC RZD RZK S16 S1Z S26 S27 S28 S3B SAP SBS SBU SCLPG SDH SDM SHX SISQX SJYHP SNE SNPRN SNX SOHCF SOJ SPISZ SRMVM SSLCW SSXJD STPWE SV3 SZN T13 T16 TEORI TN5 TSG TSK TSV TUC TUS TWZ U2A U9L UG4 UKHRP UOJIU UTJUX UZXMN VC2 VFIZW VH1 W23 W48 WH7 WIP WK6 WK8 WOW WQ9 XOL XSW YCJ YLTOR YQT YYQ Z45 Z7R Z7U Z7X Z7Z Z82 Z83 Z87 Z88 Z8M Z8O Z8R Z8T Z8V Z8W Z91 Z92 ZCA ZCG ZGI ZMTXR ZMU ZOVNA ZY4 ~8M ~A9 ~EX AAPKM AAYXX ABBRH ABDBE ABFSG ACSTC ADHKG ADXHL AEZWR AFDZB AFHIU AFOHR AGQPQ AHPBZ AHWEU AIXLP ATHPR AYFIA CITATION PHGZM PHGZT 7SW ABRTQ BJH BNH BNI BNJ BNO ERI PET PJZUB POGQB PPXIY PRQQA REK WWN CGR CUY CVF ECM EIF NPM AEIIB PMFND 7QJ 7TK 7XB 8FK AHOVV K9. MBDVC PKEHL PQEST PQUKI PRINS Q9U 7X8 5PM |
| ID | FETCH-LOGICAL-c635t-e7d913103aa80fac2b2f26f0326db3c8eef28c27fa2461c948faf2a49cc43d423 |
| IEDL.DBID | U2A |
| ISSN | 0162-3257 1573-3432 |
| IngestDate | Thu Aug 21 18:38:40 EDT 2025 Thu Jul 10 18:44:40 EDT 2025 Sat Aug 16 15:41:52 EDT 2025 Tue Jun 17 21:11:55 EDT 2025 Thu Jun 12 23:38:36 EDT 2025 Tue Jun 10 20:38:02 EDT 2025 Fri Jun 27 04:03:34 EDT 2025 Mon Jul 21 05:35:13 EDT 2025 Fri Aug 01 12:12:40 EDT 2025 Thu Apr 24 23:12:09 EDT 2025 Tue Jul 01 03:23:37 EDT 2025 Fri Feb 21 02:47:06 EST 2025 |
| IsDoiOpenAccess | false |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 11 |
| Keywords | Preschool Gastrointestinal Developmental delay Autism spectrum disorder |
| Language | English |
| License | 2021. Springer Science+Business Media, LLC, part of Springer Nature. |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c635t-e7d913103aa80fac2b2f26f0326db3c8eef28c27fa2461c948faf2a49cc43d423 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 content type line 23 Author contributions All authors gave final approval of the article and agree to be accountable for all aspects of the work, ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved. All authors made substantial contributions to the conception or design of the work; or the acquisition, analysis, or interpretation of data. All authors drafted the work or revised it critically for important intellectual content. |
| ORCID | 0000-0002-0836-746X |
| OpenAccessLink | https://www.ncbi.nlm.nih.gov/pmc/articles/8375271 |
| PMID | 33394243 |
| PQID | 2581100967 |
| PQPubID | 48401 |
| PageCount | 12 |
| ParticipantIDs | pubmedcentral_primary_oai_pubmedcentral_nih_gov_8375271 proquest_miscellaneous_2475095808 proquest_journals_2581100967 gale_infotracmisc_A678871134 gale_infotracgeneralonefile_A678871134 gale_infotracacademiconefile_A678871134 gale_incontextgauss_ISR_A678871134 pubmed_primary_33394243 eric_primary_EJ1312783 crossref_primary_10_1007_s10803_020_04786_9 crossref_citationtrail_10_1007_s10803_020_04786_9 springer_journals_10_1007_s10803_020_04786_9 |
| ProviderPackageCode | CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | 2021-11-01 |
| PublicationDateYYYYMMDD | 2021-11-01 |
| PublicationDate_xml | – month: 11 year: 2021 text: 2021-11-01 day: 01 |
| PublicationDecade | 2020 |
| PublicationPlace | New York |
| PublicationPlace_xml | – name: New York – name: United States |
| PublicationTitle | Journal of autism and developmental disorders |
| PublicationTitleAbbrev | J Autism Dev Disord |
| PublicationTitleAlternate | J Autism Dev Disord |
| PublicationYear | 2021 |
| Publisher | Springer US Springer Springer Nature B.V |
| Publisher_xml | – name: Springer US – name: Springer – name: Springer Nature B.V |
| References | Bresnahan, M., Hornig, M., Schultz, A. F., Gunnes, N., Hirtz, D., Lie, K. K., … Lipkin, W. I. (2015). Association of maternal report of infant and toddler gastrointestinal symptoms with autism: evidence from a prospective birth cohort. JAMA Psychiatry, 72(5), 466–474. doi:https://doi.org/10.1001/jamapsychiatry.2014.3034 Lord, C., Rutter, M., DiLavore, P., & Risi, S. (1999). Autism diagnostic observation schedule. Los Angeles: Western Psychological Services. AlamRAbdolmalekyHMZhouJRMicrobiome, inflammation, epigenetic alterations, and mental diseasesAmerican Journal of the Medical Genetics Part B Neuropsychiatric Genetics201710.1002/ajmg.b.32567 FungTCOlsonCAHsiaoEYInteractions between the microbiota, immune and nervous systems in health and diseaseNature Neuroscience201720214515510.1038/nn.4476280926616960010 ChaidezVHansenRLHertz-PicciottoIGastrointestinal problems in children with autism, developmental delays or typical developmentJournal of Autism and Developmental Disorders20144451117112710.1007/s10803-013-1973-x241935773981895 LewisSJHeatonKWStool form scale as a useful guide to intestinal transit timeScandinavian Journal of Gastroenterology199732992092410.3109/003655297090112039299672 Hyman, S. L., Stewart, P. A., Schmidt, B., Cain, U., Lemcke, N., Foley, J. T., … Ng, P. K. (2012). Nutrient intake from food in children with autism. Pediatrics, 130(Suppl 2), S145–153. doi:https://doi.org/10.1542/peds.2012-0900L Mazurek, M. O., Vasa, R. A., Kalb, L. G., Kanne, S. M., Rosenberg, D., Keefer, A., … Lowery, L. A. (2013). Anxiety, sensory over-responsivity, and gastrointestinal problems in children with autism spectrum disorders. J Abnorm Child Psychol, 41(1), 165-176. doi:https://doi.org/10.1007/s10802-012-9668-x WangLWTancrediDJThomasDWThe prevalence of gastrointestinal problems in children across the United States with autism spectrum disorders from families with multiple affected membersJournal of Developmental and Behavioral Pediatrics201132535136010.1097/DBP.0b013e31821bd06a21555957 OwensJAMaximRNobileCMcGuinnMMsallMParental and self-report of sleep in children with attention-deficit/hyperactivity disorderArchives of Pediatrics and Adolescent Medicine2000154654955510.1001/archpedi.154.6.549 AchenbachTChild behavior checklist. 1992BurlingtonAchenbach System of Empirically based Assessment GorrindoPWilliamsKCLeeEBWalkerLSMcGrewSGLevittPGastrointestinal dysfunction in autism: Parental report, clinical evaluation, and associated factorsAutism Res20125210110810.1002/aur.237225114503335766 Wiggins, L. D., Reynolds, A., Rice, C. E., Moody, E. J., Bernal, P., Blaskey, L., … Levy, S. E. (2015). Using standardized diagnostic instruments to classify children with autism in the study to explore early development. J Autism Dev Disord, 45(5), 1271-1280. doi:https://doi.org/10.1007/s10803-014-2287-3 CampbellDBBuieTMWinterHBaumanMSutcliffeJSPerrinJMLevittPDistinct genetic risk based on association of MET in families with co-occurring autism and gastrointestinal conditionsPediatrics200912331018102410.1542/peds.2008-081919255034 MullenEMullen scales of early learning1995San AntonioPearson Rutter, M., Bailey, A., & Lord, C. (2003). SCQ: Social communication questionnaire. Los Angeles: Western Psychological Services. Valicenti-McDermottMDMcVicarKCohenHJWershilBKShinnarSGastrointestinal symptoms in children with an autism spectrum disorder and language regressionPediatric Neurology200839639239810.1016/j.pediatrneurol.2008.07.01919027584 Ferguson, B. J., Marler, S., Altstein, L. L., Lee, E. B., Akers, J., Sohl, K., … Beversdorf, D. Q. (2017). Psychophysiological Associations with Gastrointestinal Symptomatology in Autism Spectrum Disorder. Autism Res, 10(2), 276-288. doi:https://doi.org/10.1002/aur.1646 ShumwaySFarmerCThurmAJosephLBlackDGoldenCThe ADOS calibrated severity score: Relationship to phenotypic variables and stability over timeAutism Res20125426727610.1002/aur.1238226280873422401 Reynolds, A. M., Soke, G. N., Sabourin, K. R., Hepburn, S., Katz, T., Wiggins, L. D., … Levy, S. E. (2019). Sleep problems in 2- to 5-year-olds with autism spectrum disorder and other developmental delays. Pediatrics, 143(3). doi:https://doi.org/10.1542/peds.2018-0492 Schendel, D. E., Diguiseppi, C., Croen, L. A., Fallin, M. D., Reed, P. L., Schieve, L. A., … Yeargin-Allsopp, M. (2012). The Study to Explore Early Development (SEED): A multisite epidemiologic study of autism by the Centers for Autism and Developmental Disabilities Research and Epidemiology (CADDRE) network. J Autism Dev Disord, 42(10), 2121-2140. doi:https://doi.org/10.1007/s10803-012-1461-8 TengABartleASadehAMindellJInfant and toddler sleep in Australia and New ZealandJournal of Paediatrics and Child Health201248326827310.1111/j.1440-1754.2011.02251.x22107168 Buie, T., Campbell, D. B., Fuchs, G. J., 3rd, Furuta, G. T., Levy, J., Vandewater, J., … Winter, H. (2010). Evaluation, diagnosis, and treatment of gastrointestinal disorders in individuals with ASDs: a consensus report. Pediatrics, 125(Suppl 1), S1-18. doi:https://doi.org/10.1542/peds.2009-1878C McElhanonBOMcCrackenCKarpenSSharpWGGastrointestinal symptoms in autism spectrum disorder: A meta-analysisPediatrics2014133587288310.1542/peds.2013-399524777214 LordCRutterMLe CouteurAAutism Diagnostic Interview-Revised: A revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disordersJournal of Autism and Developmental Disorders199424565968510.1007/BF02172145 AldingerKALaneCJVeenstra-VanderWeeleJLevittPPatterns of risk for multiple co-occurring medical conditions replicate across distinct cohorts of children with autism spectrum disorderAutism Res20158677178110.1002/aur.1492260110864736680 Doshi-VelezFGeYKohaneIComorbidity clusters in autism spectrum disorders: An electronic health record time-series analysisPediatrics20141331e546310.1542/peds.2013-0819243239953876178 OwensJASpiritoAMcGuinnMThe children's sleep habits questionnaire (CSHQ): Psychometric properties of a survey instrument for school-aged childrenSleep20002381043105110.1093/sleep/23.8.1d KushakRIBuieTMMurrayKFNewburgDSChenCNestoridiEWinterHSEvaluation of intestinal function in children with autism and gastrointestinal symptomsJournal of Pediatric Gastroenterology and Nutrition201662568769110.1097/MPG.000000000000117426913756 RussoMMartinelliMSciorioEBottaCMieleEValloneGStaianoAStool consistency, but not frequency, correlates with total gastrointestinal transit time in childrenJournal of Pediatrics201316261188119210.1016/j.jpeds.2012.11.082 4786_CR5 KA Aldinger (4786_CR3) 2015; 8 4786_CR9 JA Owens (4786_CR21) 2000; 23 R Alam (4786_CR2) 2017 MD Valicenti-McDermott (4786_CR28) 2008; 39 4786_CR22 4786_CR24 4786_CR4 A Teng (4786_CR27) 2012; 48 M Russo (4786_CR23) 2013; 162 4786_CR25 JA Owens (4786_CR20) 2000; 154 T Achenbach (4786_CR1) 1992 P Gorrindo (4786_CR11) 2012; 5 BO McElhanon (4786_CR18) 2014; 133 SJ Lewis (4786_CR14) 1997; 32 F Doshi-Velez (4786_CR8) 2014; 133 4786_CR12 C Lord (4786_CR15) 1994; 24 4786_CR30 S Shumway (4786_CR26) 2012; 5 RI Kushak (4786_CR13) 2016; 62 LW Wang (4786_CR29) 2011; 32 4786_CR16 4786_CR17 V Chaidez (4786_CR7) 2014; 44 TC Fung (4786_CR10) 2017; 20 E Mullen (4786_CR19) 1995 DB Campbell (4786_CR6) 2009; 123 |
| References_xml | – reference: Valicenti-McDermottMDMcVicarKCohenHJWershilBKShinnarSGastrointestinal symptoms in children with an autism spectrum disorder and language regressionPediatric Neurology200839639239810.1016/j.pediatrneurol.2008.07.01919027584 – reference: AldingerKALaneCJVeenstra-VanderWeeleJLevittPPatterns of risk for multiple co-occurring medical conditions replicate across distinct cohorts of children with autism spectrum disorderAutism Res20158677178110.1002/aur.1492260110864736680 – reference: KushakRIBuieTMMurrayKFNewburgDSChenCNestoridiEWinterHSEvaluation of intestinal function in children with autism and gastrointestinal symptomsJournal of Pediatric Gastroenterology and Nutrition201662568769110.1097/MPG.000000000000117426913756 – reference: Mazurek, M. O., Vasa, R. A., Kalb, L. G., Kanne, S. M., Rosenberg, D., Keefer, A., … Lowery, L. A. (2013). Anxiety, sensory over-responsivity, and gastrointestinal problems in children with autism spectrum disorders. J Abnorm Child Psychol, 41(1), 165-176. doi:https://doi.org/10.1007/s10802-012-9668-x – reference: Rutter, M., Bailey, A., & Lord, C. (2003). SCQ: Social communication questionnaire. Los Angeles: Western Psychological Services. – reference: LordCRutterMLe CouteurAAutism Diagnostic Interview-Revised: A revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disordersJournal of Autism and Developmental Disorders199424565968510.1007/BF02172145 – reference: CampbellDBBuieTMWinterHBaumanMSutcliffeJSPerrinJMLevittPDistinct genetic risk based on association of MET in families with co-occurring autism and gastrointestinal conditionsPediatrics200912331018102410.1542/peds.2008-081919255034 – reference: Schendel, D. E., Diguiseppi, C., Croen, L. A., Fallin, M. D., Reed, P. L., Schieve, L. A., … Yeargin-Allsopp, M. (2012). The Study to Explore Early Development (SEED): A multisite epidemiologic study of autism by the Centers for Autism and Developmental Disabilities Research and Epidemiology (CADDRE) network. J Autism Dev Disord, 42(10), 2121-2140. doi:https://doi.org/10.1007/s10803-012-1461-8 – reference: Wiggins, L. D., Reynolds, A., Rice, C. E., Moody, E. J., Bernal, P., Blaskey, L., … Levy, S. E. (2015). Using standardized diagnostic instruments to classify children with autism in the study to explore early development. J Autism Dev Disord, 45(5), 1271-1280. doi:https://doi.org/10.1007/s10803-014-2287-3 – reference: Bresnahan, M., Hornig, M., Schultz, A. F., Gunnes, N., Hirtz, D., Lie, K. K., … Lipkin, W. I. (2015). Association of maternal report of infant and toddler gastrointestinal symptoms with autism: evidence from a prospective birth cohort. JAMA Psychiatry, 72(5), 466–474. doi:https://doi.org/10.1001/jamapsychiatry.2014.3034 – reference: Buie, T., Campbell, D. B., Fuchs, G. J., 3rd, Furuta, G. T., Levy, J., Vandewater, J., … Winter, H. (2010). Evaluation, diagnosis, and treatment of gastrointestinal disorders in individuals with ASDs: a consensus report. Pediatrics, 125(Suppl 1), S1-18. doi:https://doi.org/10.1542/peds.2009-1878C – reference: GorrindoPWilliamsKCLeeEBWalkerLSMcGrewSGLevittPGastrointestinal dysfunction in autism: Parental report, clinical evaluation, and associated factorsAutism Res20125210110810.1002/aur.237225114503335766 – reference: AlamRAbdolmalekyHMZhouJRMicrobiome, inflammation, epigenetic alterations, and mental diseasesAmerican Journal of the Medical Genetics Part B Neuropsychiatric Genetics201710.1002/ajmg.b.32567 – reference: FungTCOlsonCAHsiaoEYInteractions between the microbiota, immune and nervous systems in health and diseaseNature Neuroscience201720214515510.1038/nn.4476280926616960010 – reference: Reynolds, A. M., Soke, G. N., Sabourin, K. R., Hepburn, S., Katz, T., Wiggins, L. D., … Levy, S. E. (2019). Sleep problems in 2- to 5-year-olds with autism spectrum disorder and other developmental delays. Pediatrics, 143(3). doi:https://doi.org/10.1542/peds.2018-0492 – reference: ShumwaySFarmerCThurmAJosephLBlackDGoldenCThe ADOS calibrated severity score: Relationship to phenotypic variables and stability over timeAutism Res20125426727610.1002/aur.1238226280873422401 – reference: WangLWTancrediDJThomasDWThe prevalence of gastrointestinal problems in children across the United States with autism spectrum disorders from families with multiple affected membersJournal of Developmental and Behavioral Pediatrics201132535136010.1097/DBP.0b013e31821bd06a21555957 – reference: ChaidezVHansenRLHertz-PicciottoIGastrointestinal problems in children with autism, developmental delays or typical developmentJournal of Autism and Developmental Disorders20144451117112710.1007/s10803-013-1973-x241935773981895 – reference: Ferguson, B. J., Marler, S., Altstein, L. L., Lee, E. B., Akers, J., Sohl, K., … Beversdorf, D. Q. (2017). Psychophysiological Associations with Gastrointestinal Symptomatology in Autism Spectrum Disorder. Autism Res, 10(2), 276-288. doi:https://doi.org/10.1002/aur.1646 – reference: AchenbachTChild behavior checklist. 1992BurlingtonAchenbach System of Empirically based Assessment – reference: OwensJAMaximRNobileCMcGuinnMMsallMParental and self-report of sleep in children with attention-deficit/hyperactivity disorderArchives of Pediatrics and Adolescent Medicine2000154654955510.1001/archpedi.154.6.549 – reference: Doshi-VelezFGeYKohaneIComorbidity clusters in autism spectrum disorders: An electronic health record time-series analysisPediatrics20141331e546310.1542/peds.2013-0819243239953876178 – reference: Lord, C., Rutter, M., DiLavore, P., & Risi, S. (1999). Autism diagnostic observation schedule. Los Angeles: Western Psychological Services. – reference: TengABartleASadehAMindellJInfant and toddler sleep in Australia and New ZealandJournal of Paediatrics and Child Health201248326827310.1111/j.1440-1754.2011.02251.x22107168 – reference: Hyman, S. L., Stewart, P. A., Schmidt, B., Cain, U., Lemcke, N., Foley, J. T., … Ng, P. K. (2012). Nutrient intake from food in children with autism. Pediatrics, 130(Suppl 2), S145–153. doi:https://doi.org/10.1542/peds.2012-0900L – reference: MullenEMullen scales of early learning1995San AntonioPearson – reference: McElhanonBOMcCrackenCKarpenSSharpWGGastrointestinal symptoms in autism spectrum disorder: A meta-analysisPediatrics2014133587288310.1542/peds.2013-399524777214 – reference: RussoMMartinelliMSciorioEBottaCMieleEValloneGStaianoAStool consistency, but not frequency, correlates with total gastrointestinal transit time in childrenJournal of Pediatrics201316261188119210.1016/j.jpeds.2012.11.082 – reference: OwensJASpiritoAMcGuinnMThe children's sleep habits questionnaire (CSHQ): Psychometric properties of a survey instrument for school-aged childrenSleep20002381043105110.1093/sleep/23.8.1d – reference: LewisSJHeatonKWStool form scale as a useful guide to intestinal transit timeScandinavian Journal of Gastroenterology199732992092410.3109/003655297090112039299672 – volume: 133 start-page: 872 issue: 5 year: 2014 ident: 4786_CR18 publication-title: Pediatrics doi: 10.1542/peds.2013-3995 – volume: 39 start-page: 392 issue: 6 year: 2008 ident: 4786_CR28 publication-title: Pediatric Neurology doi: 10.1016/j.pediatrneurol.2008.07.019 – volume: 23 start-page: 1043 issue: 8 year: 2000 ident: 4786_CR21 publication-title: Sleep doi: 10.1093/sleep/23.8.1d – ident: 4786_CR4 doi: 10.1001/jamapsychiatry.2014.3034 – ident: 4786_CR9 doi: 10.1002/aur.1646 – ident: 4786_CR25 doi: 10.1007/s10803-012-1461-8 – volume: 5 start-page: 267 issue: 4 year: 2012 ident: 4786_CR26 publication-title: Autism Res doi: 10.1002/aur.1238 – ident: 4786_CR12 doi: 10.1542/peds.2012-0900L – volume-title: Mullen scales of early learning year: 1995 ident: 4786_CR19 – year: 2017 ident: 4786_CR2 publication-title: American Journal of the Medical Genetics Part B Neuropsychiatric Genetics doi: 10.1002/ajmg.b.32567 – volume: 123 start-page: 1018 issue: 3 year: 2009 ident: 4786_CR6 publication-title: Pediatrics doi: 10.1542/peds.2008-0819 – volume: 20 start-page: 145 issue: 2 year: 2017 ident: 4786_CR10 publication-title: Nature Neuroscience doi: 10.1038/nn.4476 – volume: 24 start-page: 659 issue: 5 year: 1994 ident: 4786_CR15 publication-title: Journal of Autism and Developmental Disorders doi: 10.1007/BF02172145 – ident: 4786_CR16 doi: 10.1037/t17256-000 – volume: 133 start-page: e54 issue: 1 year: 2014 ident: 4786_CR8 publication-title: Pediatrics doi: 10.1542/peds.2013-0819 – volume: 48 start-page: 268 issue: 3 year: 2012 ident: 4786_CR27 publication-title: Journal of Paediatrics and Child Health doi: 10.1111/j.1440-1754.2011.02251.x – volume: 154 start-page: 549 issue: 6 year: 2000 ident: 4786_CR20 publication-title: Archives of Pediatrics and Adolescent Medicine doi: 10.1001/archpedi.154.6.549 – volume: 32 start-page: 351 issue: 5 year: 2011 ident: 4786_CR29 publication-title: Journal of Developmental and Behavioral Pediatrics doi: 10.1097/DBP.0b013e31821bd06a – volume: 62 start-page: 687 issue: 5 year: 2016 ident: 4786_CR13 publication-title: Journal of Pediatric Gastroenterology and Nutrition doi: 10.1097/MPG.0000000000001174 – volume: 32 start-page: 920 issue: 9 year: 1997 ident: 4786_CR14 publication-title: Scandinavian Journal of Gastroenterology doi: 10.3109/00365529709011203 – volume-title: Child behavior checklist. year: 1992 ident: 4786_CR1 – ident: 4786_CR5 doi: 10.1542/peds.2009-1878C – volume: 5 start-page: 101 issue: 2 year: 2012 ident: 4786_CR11 publication-title: Autism Res doi: 10.1002/aur.237 – volume: 44 start-page: 1117 issue: 5 year: 2014 ident: 4786_CR7 publication-title: Journal of Autism and Developmental Disorders doi: 10.1007/s10803-013-1973-x – ident: 4786_CR17 doi: 10.1007/s10802-012-9668-x – volume: 162 start-page: 1188 issue: 6 year: 2013 ident: 4786_CR23 publication-title: Journal of Pediatrics doi: 10.1016/j.jpeds.2012.11.082 – ident: 4786_CR24 – ident: 4786_CR30 doi: 10.1007/s10803-014-2287-3 – ident: 4786_CR22 doi: 10.1542/peds.2018-0492 – volume: 8 start-page: 771 issue: 6 year: 2015 ident: 4786_CR3 publication-title: Autism Res doi: 10.1002/aur.1492 |
| SSID | ssj0009822 |
| Score | 2.4076793 |
| Snippet | Gastrointestinal symptoms (GIS) are commonly reported in children with autism spectrum disorder (ASD). This multi-site study evaluated the prevalence of GIS in... |
| SourceID | pubmedcentral proquest gale pubmed eric crossref springer |
| SourceType | Open Access Repository Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | 3806 |
| SubjectTerms | Algorithms Autism Autism Spectrum Disorder - epidemiology Autism Spectrum Disorders Autistic children Autistic Disorder Behavior Problems Behavior Rating Scales Behavioral Science and Psychology Caregivers Child Child and School Psychology Child Behavior Child Development Child, Preschool Children Communication (Thought Transfer) Complications and side effects Control Groups Demographic aspects Developmental Delays Developmental Disabilities Developmental Disabilities - diagnosis Developmental Disabilities - epidemiology Developmentally delayed children Diagnosis Diaries Disease Control Down Syndrome Etiology Gastrointestinal diseases Gastrointestinal Diseases - diagnosis Gastrointestinal Diseases - epidemiology Health aspects Health care management Humans Meta Analysis Neurosciences Original Paper Pain Parent Surveys Pediatrics Pervasive Developmental Disorders Preschool Children Prevalence Psychology Public Health Questionnaires Risk factors Sleep Sleep disorders Symptoms (Individual Disorders) World Problems |
| SummonAdditionalLinks | – databaseName: Health & Medical Collection dbid: 7X7 link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1Lb9QwELagSKgXBAuF0IICQnAAq4mdh31CVdVSKhUkSqXlZBzHLpXaZNtkD_vvmUm82WYFPXuyij3Pjb_5hpB3LIWcUYqSMucY_EFxCRVSaKS7yxgzhjOJ3cgn37Kjs-R4mk79B7fGwyqXMbEL1GVt8Bv5LksFspvJLP88u6Y4NQpvV_0IjfvkAVKXIaQrn-Yr0l3R3yLEGaMcbNM3zfjWOYFIIobgxlxkVI4Sk8c-r0fpW2lqHUK5do_apafDx-SRryvDvd4QnpB7tprgSGYP35iQhyf-Fn1CNoeot3hKfn_RTXtTI20EeDv-xuniatbWV014UYWMhm0dpvQXOAT9flmG-775GxehdgwRh7hAmR7MZ8OOMTm8hUV6Rs4OD37uH1E_doEaqD5aavNSxjh-TGsROW1YwRzLXASFXllwI6x1TBiWO41cdEYmwmnHdCKNSXgJ5dkW2ajqyr4goS2cg2OWpTAWsiDXURE5A35fxia2LApIvDxzZTwnOY7GuFQrNmXUkwI9qU5PSgbk4_DMrGfkuFN6C1U5SB4cw9ZwukhA3qJyFXJgVAiyOdfzplFfT3-ovQwhlnHMk4B88EKuhvcy2vcswO6QNmsk-X4ked6Thv9LcGckCN5sxstLY1M-mjRqZfsBeTMs45OIkKtsPQeZBGu_VEQiIM972xw2zTmXCUtgz_nIagcB5Bgfr1QXfzquccHzlOVxQD4t7Xv1Wv8_9Zd372KbbDKEBnUtnTtko72Z21dQ27XF686B_wItIEYS priority: 102 providerName: ProQuest |
| Title | Gastrointestinal Symptoms in 2- to 5-Year-Old Children in the Study to Explore Early Development |
| URI | https://link.springer.com/article/10.1007/s10803-020-04786-9 http://eric.ed.gov/ERICWebPortal/detail?accno=EJ1312783 https://www.ncbi.nlm.nih.gov/pubmed/33394243 https://www.proquest.com/docview/2581100967 https://www.proquest.com/docview/2475095808 https://pubmed.ncbi.nlm.nih.gov/PMC8375271 |
| Volume | 51 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwlV3fb9MwED6xTUKTEILCIDAqgxA8QKTE-eU8tqPdGNpAG5W6p5A69pi0JdOSPvS_5y5x06YaSDzlwV-iOHe2L_Z33wG85wGuGZnIbK41xx8U7dsiFinJ3YWcS-nxmLKRT07Do4l_PA2mJimsXLLdl0eS9Uy9luwmiPvDiY4YidCOt2AnoH939OIJH6ykdkVzduCG3PbQI02qzP3P6CxHhvG8OTevLU6bxMmN09N6URo_gccmmmSDxvxP4YHKe1SI2ZA2evDwxJyd92C3nesWPXjUbNexJgvpGfw6TMvqriDxCBzz9Mzzxc1tVdyU7Cpn3GZVwQL7AoeF_f06YwcmBZwaMYJkxEZcEKah9ClW6yazNUbSc5iMRz8PjmxTfMGWGINUtoqy2KUiZGkqHJ1KPuOah9rBcC-beVIopbmQPNIpKdLJ2Bc61Tz1Yyl9L8MgbQ-28yJXL4Gpmdb42eNMSIVroZc6M0dLHP2ZK13FHQvcpQ0SaZTJqUDGdbLSVCa7JWi3pLZbElvwqb3nttHl-Cd6j0zbIkfH2DWqMWLBOzJ2QkoYOVFtLtN5WSZfz8-SQUhES9f1fAs-GpAu8L1kajIXsHckntVBfuggLxvp8PuA-x0gjmnZbV46X2LmlDLhgSB9vziMLHjbNtOdxJPLVTFHjE8RYCAcYcGLxlfbTnueF_vcxz5HHS9uAaQ03m3Jr37XiuPCiwIeuRZ8Xvr76rX-_tVf_R_8NexyIgzViZ77sF3dzdUbjPiqWR-2omnUh53B8MtwTNfDi28jvA5Hpz_O-vWeR7-eBP4ADX1Ogg |
| linkProvider | Springer Nature |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1Lb9NAEB5VqQS9IAgUDAUM4nEAC3v9Wh8QKiUlaZuA-pDKyXXWu6VSa4faEcqf4jcyY6-TOoLeet6x5d2ZnZn1fvMNwCvmY8xIeWoxpRgeUJRn8YgnRHcXMCaEyyKqRh6Ogv6Rt3PsH6_An6YWhmCVjU-sHHWaC_pH_oH5nNjNoiD8NPllUdcoul1tWmjUZrErZ7_xyFZ8HHxB_b5mbLt3uNW3dFcBS2BwLS0ZppFD3bWShNsqEWzMFAuUjXlMOnYFl1IxLlioEqJaE5HHVaJY4kVCeG7qEdEBuvxVz8WjTAdWP_dG3_cXNL-8vrdwAma5uBt0mY4u1uOEXWIEpwx5YEWtUKjR1stx4UpgXAZtLt3cVgFx-y7c0ZmsuVmb3j1YkVmXmkBrwEgXbg31vX0X1uZ-dnYfTr4mRXmZE1EF-hd6x8HsYlLmF4V5lpnMMsvc9K0fuNbWt_PU3NLl5jSI2apJyMcZydTwQWlWHM3mFfTTAzi6EZWsQyfLM_kITDlWCpc5SrmQGHfdxB7bSqCnSR3hSGYb4DRrHgvNgk7NOM7jBX8z6SlGPcWVnuLIgHfzZyY1B8i10uukyrlkbwenRv1MDHhJyo2JdSMjWM9pMi2KeHCwH28GBOp0HNcz4K0WUjl-l0h0lQTOjoi6WpJvWpKnNU35vwQ3WoLoP0R7uDG2WPuvIl7sNgNezIfpScLkZTKfooxH2abPbW7Aw9o255N2XTfymIdzDltWOxcgVvP2SHb2s2I3527os9Ax4H1j34vP-v-qP75-Fs_hdv9wuBfvDUa7T2CNETCpKijdgE55OZVPMbMsx8_0djbh5KY9yF-bBoUZ |
| linkToPdf | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV3dT9RAEN8QTAgvRk_RKupq_HjQhna3H9sHYwhwciBoRJLjqbTbXSSB9qS9mPvX_Oucabc9elHeeN7ppbMzOzO9_c1vCHnNfMgZmchspjWDDxTt2SISCdLdBYxJyVmE3cgHh8Husbc39sdL5E_bC4OwyjYm1oE6KyT-R77BfIHsZlEQbmgDi_i2Pfw0-WXjBCm8aW3HaTQusq9mv-Hzrfw42gZbv2FsuPNja9c2EwZsCYm2slWYRS5O2koS4ehEspRpFmgHapos5VIopZmQLNQJ0q7JyBM60SzxIik9nnlIegDh_07IfRfPWDgO54S_ornBcANmczgXpmHHtO0JRDExBFaGIrCjXlI0uOvFDHEtRS7CNxfucOvUOLxH7pqalm42TnifLKl8gOOgDXRkQFYOzA3-gKx2EXf2gJx-TsrqqkDKCog0-BtHs8tJVVyW9DynzKZVQX37BHba_nqR0S3TeI6LULdSxEDOUKYBEipaszXTazioh-T4VgyyRpbzIlePCVWp1rDNUSakggzMEyd1tISYk7nSVcyxiNvueSwNHzqO5biI50zOaKcY7BTXdooji7zvnpk0bCA3Sq-hKTvJnT1QDSebWOQVGjdG_o0cPfksmZZlPDr6Hm8GCO90Xe5Z5J0R0gW8l0xMvwRoh5RdPcm3PcmzhrD8X4LrPUGIJLK_3DpbbCJZGc_PnUVedsv4JKLzclVMQcbDutMXjrDIo8Y3O6U555HHPNA57HltJ4D85v2V_PxnzXMueOiz0LXIh9a_56_1_11_crMWL8gKxI34y-hw_ylZZYhQqjtL18lydTVVz6DErNLn9Vmm5PS2g8dfkRaH6Q |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Gastrointestinal+Symptoms+in+2-+to+5-Year-Old+Children+in+the+Study+to+Explore+Early+Development&rft.jtitle=Journal+of+autism+and+developmental+disorders&rft.au=Reynolds%2C+Ann+M&rft.au=Soke%2C+Gnakub+N&rft.au=Sabourin%2C+Katherine+R&rft.au=Croen%2C+Lisa+A&rft.date=2021-11-01&rft.pub=Springer&rft.issn=0162-3257&rft.volume=51&rft.issue=11&rft.spage=3806&rft_id=info:doi/10.1007%2Fs10803-020-04786-9&rft.externalDocID=A678871134 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0162-3257&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0162-3257&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0162-3257&client=summon |