A meta-analysis of Th1 and Th2 cytokine profiles differentiating tuberculous from malignant pleural effusion

• Published in: Scientific Reports Vol. 12; no. 1; pp. 2743 - 10
• Main Authors: Zeng, Yulin, Wang, Liwei, Zhou, Hai, Qi, Yu
• Format: Journal Article
• Language: English
• Published: London Springer Science and Business Media LLC 17.02.2022; Nature Publishing Group UK; Nature Publishing Group; Nature Portfolio
• Subjects: 692/699/255/1856; 692/699/67/1612; Biopsy; Cytokines; Cytokines - immunology; Diagnosis, Differential; Humanities and Social Sciences; Humans; Immune response; Interleukin 10; Interleukin 4; Lymphocytes T; Medicine; Meta-analysis; multidisciplinary; Pleural effusion; Pleural Effusion, Malignant; Pleural Effusion, Malignant - diagnosis; Pleural Effusion, Malignant - immunology; Q; R; Science; Science (multidisciplinary); Th1 Cells; Th1 Cells - immunology; Th2 Cells; Th2 Cells - immunology; Tissue culture; Tuberculosis; Tuberculosis, Pleural; Tuberculosis, Pleural - diagnosis; Tuberculosis, Pleural - immunology; Tumor necrosis factor-α; γ-Interferon

To clarify the predominance of Th1 or Th2 immune responses in malignant and tuberculous pleural effusion (MPE and TPE, respectively), we performed a meta-analysis of previously published results of the levels of Th1/Th2 cytokines associated with these two types of pleural effusion to evaluate the us...