Precision Medicine for Breast Cancer: The Paths to Truly Individualized Diagnosis and Treatment

Precision medicine in oncology seeks to individualize each patient’s treatment regimen based on an accurate assessment of the risk of recurrence or progression of that person’s cancer. Precision will be achieved at each phase of care, from detection to diagnosis to surgery, systemic therapy, and rad...

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Published inInternational journal of breast cancer Vol. 2018; no. 2018; pp. 1 - 8
Main Author Harris, Eleanor E. R.
Format Journal Article
LanguageEnglish
Published Cairo, Egypt Hindawi Publishing Corporation 01.01.2018
Hindawi
Hindawi Limited
Wiley
Subjects
Biology
Body mass index
Breast cancer
Cancer therapies
Care and treatment
Clinical trials
Consortia
Development and progression
Diagnosis
Disease
Health risk assessment
Mammography
Medical research
Molecular biology
Oncology
Patients
Population
Precision medicine
Radiation (Physics)
Radiation therapy
Radiology
Radiotherapy
Review
Studies
Surgery
Surveillance
Taxonomy
Tumors
United States
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Abstract Precision medicine in oncology seeks to individualize each patient’s treatment regimen based on an accurate assessment of the risk of recurrence or progression of that person’s cancer. Precision will be achieved at each phase of care, from detection to diagnosis to surgery, systemic therapy, and radiation therapy, to survivorship and follow-up care. The precision arises from detailed knowledge of the inherent biological propensities of each tumor, rather than generalizing treatment approaches based on phenotypic, or even genotypic, categories. Extensive research is being conducted in multiple disciplines, including radiology, pathology, molecular biology, and surgical, medical, and radiation oncology. Clinical trial design is adapting to the new paradigms and moving away from grouping heterogeneous patient populations into limited treatment comparison arms. This review touches on several areas invested in clinical research. This special issue highlights the specific work of a number of groups working on precision medicine for breast cancer.
AbstractList Precision medicine in oncology seeks to individualize each patient’s treatment regimen based on an accurate assessment of the risk of recurrence or progression of that person’s cancer. Precision will be achieved at each phase of care, from detection to diagnosis to surgery, systemic therapy, and radiation therapy, to survivorship and follow-up care. The precision arises from detailed knowledge of the inherent biological propensities of each tumor, rather than generalizing treatment approaches based on phenotypic, or even genotypic, categories. Extensive research is being conducted in multiple disciplines, including radiology, pathology, molecular biology, and surgical, medical, and radiation oncology. Clinical trial design is adapting to the new paradigms and moving away from grouping heterogeneous patient populations into limited treatment comparison arms. This review touches on several areas invested in clinical research. This special issue highlights the specific work of a number of groups working on precision medicine for breast cancer.
Audience Academic
Author Harris, Eleanor E. R.
AuthorAffiliation Department of Radiation Oncology, Case Western Reserve University and University Hospitals, Cleveland, OH, USA
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BackLink https://www.ncbi.nlm.nih.gov/pubmed/29862084$$D View this record in MEDLINE/PubMed
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ContentType Journal Article
Copyright Copyright © 2018 Eleanor E. R. Harris.
COPYRIGHT 2018 Hindawi Limited
Copyright © 2018 Eleanor E. R. Harris.; This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright © 2018 Eleanor E. R. Harris. 2018
Copyright_xml – notice: Copyright © 2018 Eleanor E. R. Harris.
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– notice: Copyright © 2018 Eleanor E. R. Harris.; This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
– notice: Copyright © 2018 Eleanor E. R. Harris. 2018
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Snippet Precision medicine in oncology seeks to individualize each patient’s treatment regimen based on an accurate assessment of the risk of recurrence or progression...
Precision medicine in oncology seeks to individualize each patient's treatment regimen based on an accurate assessment of the risk of recurrence or progression...
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SubjectTerms Biology
Body mass index
Breast cancer
Cancer therapies
Care and treatment
Clinical trials
Consortia
Development and progression
Diagnosis
Disease
Health risk assessment
Mammography
Medical research
Molecular biology
Oncology
Patients
Population
Precision medicine
Radiation (Physics)
Radiation therapy
Radiology
Radiotherapy
Review
Studies
Surgery
Surveillance
Taxonomy
Tumors
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Title Precision Medicine for Breast Cancer: The Paths to Truly Individualized Diagnosis and Treatment
URI https://search.emarefa.net/detail/BIM-1169451
https://dx.doi.org/10.1155/2018/4809183
https://www.ncbi.nlm.nih.gov/pubmed/29862084
https://www.proquest.com/docview/2041556454/abstract/
https://search.proquest.com/docview/2049938341
https://pubmed.ncbi.nlm.nih.gov/PMC5971283
https://doaj.org/article/5609b9af9d394f75b62e3058fd4e82ed
Volume 2018
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