Precision Medicine for Breast Cancer: The Paths to Truly Individualized Diagnosis and Treatment

Precision medicine in oncology seeks to individualize each patient’s treatment regimen based on an accurate assessment of the risk of recurrence or progression of that person’s cancer. Precision will be achieved at each phase of care, from detection to diagnosis to surgery, systemic therapy, and rad...

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Bibliographic Details
Published inInternational journal of breast cancer Vol. 2018; no. 2018; pp. 1 - 8
Main Author Harris, Eleanor E. R.
Format Journal Article
LanguageEnglish
Published Cairo, Egypt Hindawi Publishing Corporation 01.01.2018
Hindawi
John Wiley & Sons, Inc
Hindawi Limited
Subjects
Biology
Body mass index
Breast cancer
Cancer therapies
Care and treatment
Clinical trials
Consortia
Development and progression
Diagnosis
Disease
Health risk assessment
Mammography
Medical research
Oncology
Patients
Population
Precision medicine
Radiation therapy
Review
Studies
Surveillance
Taxonomy
United States
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Summary:Precision medicine in oncology seeks to individualize each patient’s treatment regimen based on an accurate assessment of the risk of recurrence or progression of that person’s cancer. Precision will be achieved at each phase of care, from detection to diagnosis to surgery, systemic therapy, and radiation therapy, to survivorship and follow-up care. The precision arises from detailed knowledge of the inherent biological propensities of each tumor, rather than generalizing treatment approaches based on phenotypic, or even genotypic, categories. Extensive research is being conducted in multiple disciplines, including radiology, pathology, molecular biology, and surgical, medical, and radiation oncology. Clinical trial design is adapting to the new paradigms and moving away from grouping heterogeneous patient populations into limited treatment comparison arms. This review touches on several areas invested in clinical research. This special issue highlights the specific work of a number of groups working on precision medicine for breast cancer.
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Academic Editor: Robert-Alain Toillon
ISSN:2090-3170
2090-3189
2090-3189
DOI:10.1155/2018/4809183