Microbiota in neuroinflammation and synaptic dysfunction: a focus on Alzheimer’s disease

• Published in: Molecular neurodegeneration Vol. 17; no. 1; pp. 19 - 23
• Main Authors: Bairamian, Diane, Sha, Sha, Rolhion, Nathalie, Sokol, Harry, Dorothée, Guillaume, Lemere, Cynthia A., Krantic, Slavica
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 05.03.2022; BioMed Central; BMC
• Subjects: Alzheimer Disease - pathology; Alzheimer's disease; Analysis; Brain - pathology; Cognitive Dysfunction - pathology; Gastrointestinal Microbiome - physiology; Gut microbiota; Gut microbiota, Synaptic dysfunction, Alzheimer’s disease, Peripheral immunomodulation, Neuroinflammation; Humans; Inflammation; Life Sciences; Medical research; Medicine, Experimental; Microbiota; Microbiota (Symbiotic organisms); Neuroinflammation; Neuroinflammatory Diseases; Neurons; Neurophysiology; Peripheral immunomodulation; Review; Synaptic dysfunction; Gut microbiota; Neuroinflammation; Alzheimer’s disease; Peripheral immunomodulation; Synaptic dysfunction; Gut microbiota Synaptic dysfunction Alzheimer's disease Peripheral immunomodulation Neuroinflammation; Alzheimer's disease

The implication of gut microbiota in the control of brain functions in health and disease is a novel, currently emerging concept. Accumulating data suggest that the gut microbiota exert its action at least in part by modulating neuroinflammation. Given the link between neuroinflammatory changes and...