Efficacy and safety of olmesartan medoxomil plus amlodipine in age, gender and hypertension severity defined subgroups of hypertensive patients

• Published in: Journal of human hypertension Vol. 25; no. 6; pp. 354 - 363
• Main Authors: Schmieder, R E, Böhm, M
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.06.2011; Nature Publishing Group
• Subjects: 631/92/436/108; 692/699/75/243; 692/700/565/1436/1437; Age; Age Factors; Aged; Amlodipine; Amlodipine - adverse effects; Amlodipine - pharmacology; Amlodipine - therapeutic use; Antihypertensive Agents - adverse effects; Antihypertensive Agents - pharmacology; Antihypertensive Agents - therapeutic use; Antihypertensives; Arterial hypertension. Arterial hypotension; Biological and medical sciences; Blood and lymphatic vessels; Blood pressure; Blood Pressure - drug effects; Blood Pressure - physiology; Cardiology. Vascular system; Clinical manifestations. Epidemiology. Investigative techniques. Etiology; Diagnosis; Diuretics; Dosage and administration; Double-Blind Method; Drug therapy; Drug Therapy, Combination; Epidemiology; Female; Females; Gender; Health Administration; Humans; Hypertension; Hypertension - drug therapy; Hypertension - physiopathology; Imidazoles - adverse effects; Imidazoles - pharmacology; Imidazoles - therapeutic use; Male; Males; Medical sciences; Medicine; Medicine & Public Health; Middle Aged; Olmesartan Medoxomil; original-article; Public Health; Severity of Illness Index; Sex Factors; Statistical analysis; Tetrazoles - adverse effects; Tetrazoles - pharmacology; Tetrazoles - therapeutic use; Treatment Outcome; Germany; olmesartan/amlodipine; blood pressure; patient subgroups; Antianginal agent; Human; Hypertension; Tetrazole derivatives; Calcium antagonist; Peptide hormone; Cardiovascular disease; Olmesartan medoxomil; Octapeptide; Amlodipine; Antihypertensive agent; Arterial pressure; Dihydropyridine derivatives; Sartan derivatives; Blood pressure; Angiotensin antagonist; Angiotensin II

Effective antihypertensive therapy is crucial for preventing cardiovascular events; however, blood pressure (BP) control rates remain poor. The objective of this analysis was to determine the efficacy of olmesartan/amlodipine in age, severity and gender-based subgroups of patients with moderate-to-s...