Discrete particle simulations predicting mixing behavior of solid substrate particles in a rotating drum fermenter

• Published in: Biotechnology and bioengineering Vol. 75; no. 6; pp. 666 - 675
• Main Authors: Schutyser, M. A. I., Padding, J. T., Weber, F. J., Briels, W. J., Rinzema, A., Boom, R.
• Format: Journal Article
• Language: English
• Published: New York John Wiley & Sons, Inc 20.12.2001; Wiley
• Subjects: Biological and medical sciences; Bioreactors; Biotechnology; Computer simulation; discrete particle simulations; Entropy; Fermentation; Fundamental and applied biological sciences. Psychology; Image analysis; Methods. Procedures. Technologies; Microbial engineering. Fermentation and microbial culture technology; mixing; scale-up baffles; Sectie Proceskunde; solid-state fermentation; Sub-department of Food and Bioprocess Engineering; Substrates; VLAG; Dimensioning; Solid substrate fermentation; Agitation; Mixing; Solid particle; Simulation

A soft‐sphere discrete particle model was used to simulate mixing behavior of solid substrate particles in a slow rotating drum for solid‐state fermentation. In this approach, forces acting on and subsequent motion of individual particles can be predicted. The (2D) simulations were qualitatively and...