Discrete particle simulations predicting mixing behavior of solid substrate particles in a rotating drum fermenter
A soft‐sphere discrete particle model was used to simulate mixing behavior of solid substrate particles in a slow rotating drum for solid‐state fermentation. In this approach, forces acting on and subsequent motion of individual particles can be predicted. The (2D) simulations were qualitatively and...
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Published in | Biotechnology and bioengineering Vol. 75; no. 6; pp. 666 - 675 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
New York
John Wiley & Sons, Inc
20.12.2001
Wiley |
Subjects | |
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Abstract | A soft‐sphere discrete particle model was used to simulate mixing behavior of solid substrate particles in a slow rotating drum for solid‐state fermentation. In this approach, forces acting on and subsequent motion of individual particles can be predicted. The (2D) simulations were qualitatively and quantitatively validated by mixing experiments using video and image analysis techniques. It was found that the simulations successfully predicted the mixing progress as a function of the degree of filling and size of the drum. It is shown that only relatively large, straight baffles perpendicular to the drum wall (67% of the drum radius) increase the mixing performance of the rotating drum. Considering the different aspects of mixing dealt with in this work, it is concluded that the soft sphere discrete particle model can serve as a valuable tool for investigating mixing of solid substrate particles. Finally, it is expected that this model may evolve into a potential tool for design and scale‐up of mixed solid‐state fermenters. © 2001 John Wiley & Sons, Inc. Biotechnol Bioeng 75: 666–675, 2001. |
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AbstractList | Abstract
A soft‐sphere discrete particle model was used to simulate mixing behavior of solid substrate particles in a slow rotating drum for solid‐state fermentation. In this approach, forces acting on and subsequent motion of individual particles can be predicted. The (2D) simulations were qualitatively and quantitatively validated by mixing experiments using video and image analysis techniques. It was found that the simulations successfully predicted the mixing progress as a function of the degree of filling and size of the drum. It is shown that only relatively large, straight baffles perpendicular to the drum wall (67% of the drum radius) increase the mixing performance of the rotating drum. Considering the different aspects of mixing dealt with in this work, it is concluded that the soft sphere discrete particle model can serve as a valuable tool for investigating mixing of solid substrate particles. Finally, it is expected that this model may evolve into a potential tool for design and scale‐up of mixed solid‐state fermenters. © 2001 John Wiley & Sons, Inc. Biotechnol Bioeng 75: 666–675, 2001. A soft‐sphere discrete particle model was used to simulate mixing behavior of solid substrate particles in a slow rotating drum for solid‐state fermentation. In this approach, forces acting on and subsequent motion of individual particles can be predicted. The (2D) simulations were qualitatively and quantitatively validated by mixing experiments using video and image analysis techniques. It was found that the simulations successfully predicted the mixing progress as a function of the degree of filling and size of the drum. It is shown that only relatively large, straight baffles perpendicular to the drum wall (67% of the drum radius) increase the mixing performance of the rotating drum. Considering the different aspects of mixing dealt with in this work, it is concluded that the soft sphere discrete particle model can serve as a valuable tool for investigating mixing of solid substrate particles. Finally, it is expected that this model may evolve into a potential tool for design and scale‐up of mixed solid‐state fermenters. © 2001 John Wiley & Sons, Inc. Biotechnol Bioeng 75: 666–675, 2001. A soft-sphere discrete particle model was used to simulate mixing behavior of solid substrate particles in a slow rotating drum for solid-state fermentation. In this approach, forces acting on and subsequent motion of individual particles can be predicted. The (2D) simulations were qualitatively and quantitatively validated by mixing experiments using video and image analysis techniques. It was found that the simulations successfully predicted the mixing progress as a function of the degree of filling and size of the drum. It is shown that only relatively large, straight baffles perpendicular to the drum wall (67% of the drum radius) increase the mixing performance of the rotating drum. Considering the different aspects of mixing dealt with in this work, it is concluded that the soft sphere discrete particle model can serve as a valuable tool for investigating mixing of solid substrate particles. Finally, it is expected that this model may evolve into a potential tool for design and scale-up of mixed solid-state fermenters. A soft-sphere discrete particle model was used to simulate mixing behavior of solid substrate particles in a slow rotating drum for solid-state fermentation. In this approach, forces acting on and subsequent motion of individual particles can be predicted. The (2D) simulations were qualitatively and quantitatively validated by mixing experiments using video and image analysis techniques. It was found that the simulations successfully predicted the mixing progress as a function of the degree of filling and size of the drum. It is shown that only relatively large, straight baffles perpendicular to the drum wall (67% of the drum radius) increase the mixing performance of the rotating drum. Considering the different aspects of mixing dealt with in this work, it is concluded that the soft sphere discrete particle model can serve as a valuable tool for investigating mixing of solid substrate particles. Finally, it is expected that this model may evolve into a potential tool for design and scale-up of mixed solid-state fermenters. copyright 2001 John Wiley & Sons, Inc. A soft-sphere discrete particle model was used to simulate mixing behavior of solid substrate particles in a slow rotating drum for solid-state fermentation. In this approach, forces acting on and subsequent motion of individual particles can be predicted. The (2D) simulations were qualitatively and quantitatively validated by mixing experiments using video and image analysis techniques. It was found that the simulations successfully predicted the mixing progress as a function of the degree of filling and size of the drum. It is shown that only relatively large, straight baffles perpendicular to the drum wall (67␘f the drum radius) increase the mixing performance of the rotating drum. Considering the different aspects of mixing dealt with in this work, it is concluded that the soft sphere discrete particle model can serve as a valuable tool for investigating mixing of solid substrate particles. Finally, it is expected that this model may evolve into a potential tool for design and scale-up of mixed solid-state fermenters |
Author | Schutyser, M. A. I. Briels, W. J. Boom, R. Padding, J. T. Weber, F. J. Rinzema, A. |
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Snippet | A soft‐sphere discrete particle model was used to simulate mixing behavior of solid substrate particles in a slow rotating drum for solid‐state fermentation.... A soft-sphere discrete particle model was used to simulate mixing behavior of solid substrate particles in a slow rotating drum for solid-state fermentation.... Abstract A soft‐sphere discrete particle model was used to simulate mixing behavior of solid substrate particles in a slow rotating drum for solid‐state... |
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SubjectTerms | Biological and medical sciences Bioreactors Biotechnology Computer simulation discrete particle simulations Entropy Fermentation Fundamental and applied biological sciences. Psychology Image analysis Methods. Procedures. Technologies Microbial engineering. Fermentation and microbial culture technology mixing scale-up baffles Sectie Proceskunde solid-state fermentation Sub-department of Food and Bioprocess Engineering Substrates VLAG |
Title | Discrete particle simulations predicting mixing behavior of solid substrate particles in a rotating drum fermenter |
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