High prevalence and characterization of extended-spectrum ß-lactamase producing Enterobacteriaceae in Chadian hospitals

• Published in: BMC infectious diseases Vol. 19; no. 1; pp. 205 - 7
• Main Authors: Ouchar Mahamat, Oumar, Lounnas, Manon, Hide, Mallorie, Dumont, Yann, Tidjani, Abelsalam, Kamougam, Kadidja, Abderrahmane, Madina, Benavides, Julio, Solassol, Jérôme, Bañuls, Anne-Laure, jean-Pierre, Hélène, Carrière, Christian, Godreuil, Sylvain
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 28.02.2019; BioMed Central; BMC
• Subjects: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents/pharmacology; Antibiotics; Bacteriology; Beta lactamases; beta-Lactamases/genetics; Care and treatment; Chad; Chad/epidemiology; Child; Child, Preschool; Clinical samples; Cross infection; Cross Infection/microbiology; DNA; DNA sequencing; Drug Resistance, Bacterial/drug effects; Drug Resistance, Bacterial/genetics; Elderly patients; Enterobacteriaceae; Enterobacteriaceae Infections/epidemiology; Enterobacteriaceae Infections/microbiology; Enterobacteriaceae/drug effects; Enterobacteriaceae/genetics; Enterobacteriaceae/pathogenicity; Enzymes; ESBL; Escherichia coli; Female; Genes; Hospital patients; Hospitals; Humans; Infection; Ionization; Lactams; Life Sciences; Male; Mass spectrometry; Microbial Sensitivity Tests; Microbiology and Parasitology; Middle Aged; Patient outcomes; Pneumonia; Prevalence; Spectroscopy; Tetracyclines; Chad; Chad; ESBL; Clinical samples; Prevalence; Enterobacteriaceae

Extended-spectrum ß-lactamase-producing Enterobacteriaceae (ESBL-PE) represent a major problem in the management of nosocomial infections. However, ESBL-PE are not systematically monitored in African countries. The aim of this study was to determine ESBL-PE prevalence in patients from three hospital...