Organoid cultures from normal and cancer-prone human breast tissues preserve complex epithelial lineages - Rosenbluth, Jennifer M.; Schackmann, Ron C. J.; Gray, G. Kenneth; Selfors, Laura M.; Li, Carman Man-Chung; Boedicker, Mackenzie; Kuiken, Hendrik J.; Richardson, Andrea; Brock, Jane; Garber, Judy; Dillon, Deborah; Sachs, Norman; et al. (Nature communications, 2020)
Keywords: 13; 13/106; 13/31; 14; 14/19; 631/1647/767; 631/532/2436; 692/420/755; Adult; BRCA1 Protein - genetics; Breast cancer; Breast Neoplasms; Cell culture; Cell Culture Techniques - methods; Cell differentiation; Cell Differentiation - genetics; Cell Differentiation - physiology; Cell Lineage - genetics; Cytometry; Epidermal Growth Factor - pharmacology; Epithelial cells; ErbB Receptors - metabolism; Female; Health risks; Humanities and Social Sciences; Humans; Mammary gland; Mammary Glands, Human - chemistry; Mammary Glands, Human - cytology; Mammary Glands, Human - metabolism; Middle Aged; multidisciplinary; Organoids; Organoids - chemistry; Organoids - cytology; Organoids - metabolism; p38 Mitogen-Activated Protein Kinases - antagonists & inhibitors; Progenitor cells; Propagation; Science; Science (multidisciplinary); Single-Cell Analysis; Stem cells; Stem Cells - chemistry; Stem Cells - cytology; Stem Cells - metabolism; Tissues; Transforming Growth Factor beta - antagonists & inhibitors; Young Adult