Momordica charantia fruit reduces plasma fructosamine whereas stems and leaves increase plasma insulin in adult mildly diabetic obese Göttingen Minipigs

• Published in: PloS one Vol. 19; no. 3; p. e0298163
• Main Authors: Koopmans, Sietse Jan, Binnendijk, Gisabeth, Ledoux, Allison, Choi, Young Hae, Mes, Jurriaan J., Guan, Xiaonan, Molist, Francesc, Thị Minh, Tâm Phạm, van der Wielen, Nikkie
• Format: Journal Article Web Resource
• Language: English
• Published: United States Public Library of Science 18.03.2024; Public Library of Science (PLoS)
• Subjects: Biology and Life Sciences; Bitter melon; Blood sugar; Body weight; Comparative analysis; diabete; Ethylenediaminetetraacetic acid; Fructose; Health aspects; Insulin; Life sciences; Medicine and Health Sciences; Minipigs; Momordica; Multidisciplinary; Médecine vétérinaire & santé animale; Physical Sciences; Research and Analysis Methods; Sciences du vivant; Streptozocin; Swine; Type 2 diabetes; Veterinary medicine & animal health; Netherlands; Germany

Traditionally Momordica charantia (Bitter gourd) is known for its blood glucose lowering potential. This has been validated by many previous studies based on rodent models but human trials are less convincing and the physiological mechanisms underlying the bioactivity of Bitter gourd are still uncle...