ZCCHC3 is a co-sensor of cGAS for dsDNA recognition in innate immune response - Lian, Huan; Wei, Jin; Zang, Ru; Ye, Wen; Yang, Qing; Zhang, Xia-Nan; Chen, Yun-Da; Fu, Yu-Zhi; Hu, Ming-Ming; Lei, Cao-Qi; Luo, Wei-Wei; Li, Shu; et al. (Nature communications, 2018)
Keywords: 13/106; 13/109; 13/89; 14/19; 38/77; 42/109; 631/250/2499; 631/250/262; 631/326/596/2553; 692/420/254; 96; 96/1; 96/95; AMP; Animals; Binding; Chemical synthesis; Cyclic GMP; Cytosol; Deoxyribonucleic acid; DNA; DNA - genetics; DNA - metabolism; DNA viruses; Herpes simplex; Humanities and Social Sciences; Immune response; Immune system; Immunity, Innate - genetics; Immunity, Innate - physiology; Infections; Innate immunity; Mice; Mice, Knockout; multidisciplinary; Nucleotides, Cyclic - metabolism; Nucleotidyltransferases - genetics; Nucleotidyltransferases - metabolism; Proteins; Recognition; RNA Nucleotidyltransferases - genetics; RNA Nucleotidyltransferases - metabolism; Science; Signal Transduction - genetics; Signal Transduction - physiology; Viral infections; Viruses; Zinc; Zinc finger proteins