Novel Radiobiological Gamma Index for Evaluation of 3-Dimensional Predicted Dose Distribution

• Published in: International journal of radiation oncology, biology, physics Vol. 92; no. 4; pp. 779 - 786
• Main Authors: Sumida, Iori, Yamaguchi, Hajime, Kizaki, Hisao, Aboshi, Keiko, Tsujii, Mari, Yoshikawa, Nobuhiko, Yamada, Yuji, Suzuki, Osamu, Seo, Yuji, Isohashi, Fumiaki, Yoshioka, Yasuo, Ogawa, Kazuhiko
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 15.07.2015
• Subjects: ACCURACY; Algorithms; ANIMAL TISSUES; BIOLOGICAL RADIATION EFFECTS; BLADDER; BRAIN; COMPARATIVE EVALUATIONS; ERRORS; Femur Head - radiation effects; HEAD; Head and Neck Neoplasms - radiotherapy; Hematology, Oncology and Palliative Medicine; Humans; Male; NECK; NEOPLASMS; Organs at Risk - diagnostic imaging; Organs at Risk - radiation effects; Parotid Gland - radiation effects; PATIENTS; PROBABILITY; PROSTATE; Prostate - radiation effects; Prostatic Neoplasms - radiotherapy; QUALITY ASSURANCE; Quality Assurance, Health Care; RADIATION DOSE DISTRIBUTIONS; RADIATION DOSES; Radiography; Radiology; RADIOLOGY AND NUCLEAR MEDICINE; RADIOTHERAPY; Radiotherapy Dosage; Radiotherapy Planning, Computer-Assisted - methods; Radiotherapy Planning, Computer-Assisted - standards; Radiotherapy, Intensity-Modulated - methods; Radiotherapy, Intensity-Modulated - standards; RECTUM; Rectum - radiation effects; SPINAL CORD; Urinary Bladder - radiation effects

To propose a gamma index-based dose evaluation index that integrates the radiobiological parameters of tumor control (TCP) and normal tissue complication probabilities (NTCP). Fifteen prostate and head and neck (H&N) cancer patients received intensity modulated radiation therapy. Before treatmen...