The mTOR–lysosome axis at the centre of ageing - Carosi, Julian M.; Fourrier, Célia; Bensalem, Julien; Sargeant, Timothy J. (FEBS open bio, 2022)
Keywords: Age; ageing; age‐related disease; Aging; Amino acids; Arteriosclerosis; atherosclerosis; Autophagy; Disease; DNA methylation; Humans; Kinases; Life span; longevity; lysophagy; lysosome; Lysosomes; Lysosomes - metabolism; Mechanistic Target of Rapamycin Complex 1 - metabolism; mTOR; Proteins; Rapamycin; Review; Reviews; Sensors; Signal transduction; Telomerase; TOR protein; TOR Serine-Threonine Kinases - metabolism; Transcription factors; age-related disease; mTOR; ageing; autophagy; lysophagy; lysosome