Profiling of gut microbial dysbiosis in adults with myeloid leukemia

• Published in: FEBS open bio Vol. 11; no. 7; pp. 2050 - 2059
• Main Authors: Yu, Dandan, Yu, Xiaomin, Ye, Aifang, Xu, Chunquan, Li, Xiaolong, Geng, Wujun, Zhu, Liqing, Alape‐Girón, Alberto
• Format: Journal Article
• Language: English
• Published: England John Wiley & Sons, Inc 01.07.2021; John Wiley and Sons Inc; Wiley
• Subjects: Acidobacteria; Actinobacteria; Acute myeloid leukemia; Adult; Age; Biomarkers; Chloroflexi; Chronic illnesses; Chronic myeloid leukemia; Classification; Clostridium; Dysbacteriosis; Dysbiosis; Enterococcus; Feces; Feces - microbiology; Gastrointestinal Microbiome - genetics; gene sequencing; gut microbiota; Helicobacter; Hospitals; Humans; Inflammatory diseases; Intestinal microflora; intestinal microorganisms; Lachnospiraceae; Lactobacillus; Leukemia; Leukemia, Myeloid; Megamonas; Metabolic disorders; Microbiota; Myeloid leukemia; pathogenesis; Phylogenetics; Prevotella; Principal components analysis; RNA, Ribosomal, 16S - genetics; rRNA 16S; Sphingomonas; Streptococcus; Taxonomy; Tenericutes; therapeutics; China; myeloid leukemia; pathogenesis; gene sequencing; gut microbiota

Dysregulation of gut microbiota is implicated in the pathogenesis of various diseases, including metabolic diseases, inflammatory diseases, and cancer. To date, the link between gut microbiota and myeloid leukemia (ML) remains largely unelucidated. Herein, a total of 29 patients with acute myeloid l...