TIGIT Marks Exhausted T Cells, Correlates with Disease Progression, and Serves as a Target for Immune Restoration in HIV and SIV Infection - Chew, Glen M.; Fujita, Tsuyoshi; Webb, Gabriela M.; Burwitz, Benjamin J.; Wu, Helen L.; Reed, Jason S.; Hammond, Katherine B.; Clayton, Kiera L.; Ishii, Naoto; Abdel-Mohsen, Mohamed; Liegler, Teri; Mitchell, Brooks I.; et al. (PLoS pathogens, 2016)
Keywords: Acquired immune deficiency syndrome; AIDS; Animals; B7-H1 Antigen - immunology; CD4-Positive T-Lymphocytes - immunology; CD8-Positive T-Lymphocytes - immunology; Cell Separation; Development and progression; Disease; Disease Progression; DNA, Viral - analysis; Flow Cytometry; Funding; Health aspects; HIV; HIV infection; HIV Infections - immunology; Host-virus relationships; Human immunodeficiency virus; Humans; Immune response; Infections; Lymphocyte Activation - immunology; Lymphocytes; Macaca mulatta; Mortality; Observations; Receptors, Immunologic - immunology; RNA, Viral - analysis; Simian Acquired Immunodeficiency Syndrome - immunology; Simian immunodeficiency virus; Statistical analysis; T cells; Viral infections