A systematic genetic screen identifies new factors influencing centromeric heterochromatin integrity in fission yeast

• Published in: Genome biology Vol. 15; no. 10; p. 481
• Main Authors: Bayne, Elizabeth H, Bijos, Dominika A, White, Sharon A, de Lima Alves, Flavia, Rappsilber, Juri, Allshire, Robin C
• Format: Journal Article
• Language: English
• Published: England BioMed Central 01.01.2014
• Subjects: Centromere; Gene Expression Regulation, Fungal; Heterochromatin - metabolism; RNA Interference; Schizosaccharomyces - genetics; Schizosaccharomyces pombe; Schizosaccharomyces pombe Proteins - genetics; Schizosaccharomyces pombe Proteins - metabolism; Schizosaccharomyces pombe Proteins - physiology

Heterochromatin plays important roles in the regulation and stability of eukaryotic genomes. Both heterochromatin components and pathways that promote heterochromatin assembly, including RNA interference, RNAi, are broadly conserved between the fission yeast Schizosaccharomyces pombe and humans. As...