TETRONOMYCIN, A NOVEL POLYETHER OF UNUSUAL STRUCTURE

• Published in: Journal of antibiotics Vol. 35; no. 2; pp. 142 - 150
• Main Authors: KELLER-JUSLÉN, CAMILLA, KING, HAMILTON D., KUHN, MAX, LOOSLI, HANS-RUDOLF, PACHE, WALTER, PETCHER, TREVOR J., WEBER, HANS PETER, WARTBURG, ALBERT VON
• Format: Journal Article
• Language: English
• Published: Japan JAPAN ANTIBIOTICS RESEARCH ASSOCIATION 01.01.1982
• Subjects: Anti-Bacterial Agents - isolation & purification; Anti-Bacterial Agents - pharmacology; Chemical Phenomena; Chemistry; Ethers - isolation & purification; Ethers - pharmacology; Fermentation; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Streptomyces; Streptomyces - metabolism

Tetronomycin, C34H50O8, isolated from a strain of Streptomyces sp. nov. represents a novel polycyclic ionophore polyether. The crystal structure and absolute configuration were established by X-ray analysis of the mono-O-acetyltetronomycin silver salt. Tetronomycin is the first metabolic polyether w...