Pharmacological inhibition of mTORC1 activity protects against inflammation-induced apoptosis of nucleus pulposus cells - Chen, Rigao; Yang, Fei; Wang, Yong; Wang, Xinling; Fan, Xiaohong (Brazilian journal of medical and biological research, 2021)
Keywords: Acid production; Apoptosis; BIOLOGY; Cell survival; Cytokines; Degeneration; Development and progression; Dextrose; Glucose; Glucose metabolism; Homeostasis; Humans; Inflammation; Inflammation - drug therapy; Intervertebral disc degeneration; Intervertebral Disc Degeneration - drug therapy; Intervertebral discs; Lactic acid; Mechanistic Target of Rapamycin Complex 1; MEDICINE, RESEARCH & EXPERIMENTAL; Metabolism; Metabolomics; mTORC1; Nucleus Pulposus; Nucleus pulposus cells; Physiological aspects; China; Intervertebral disc degeneration; Lactic acid; mTORC1; Nucleus pulposus cells; Apoptosis