Alzheimer's-associated PU.1 expression levels regulate microglial inflammatory response - Pimenova, Anna A.; Herbinet, Manon; Gupta, Ishaan; Machlovi, Saima I.; Bowles, Kathryn R.; Marcora, Edoardo; Goate, Alison M. (Neurobiology of disease, 2021)
Keywords: Alzheimer Disease - genetics; Alzheimer Disease - metabolism; Alzheimer's disease; Amyloid beta-Peptides - pharmacology; Amyloid β; Animals; Anti-inflammatory microglia; Apoptosis - drug effects; Apoptosis - genetics; Cell Line; Cytokines - drug effects; Cytokines - metabolism; Disease-associated microglia; Gene Expression Profiling; Gene Knockdown Techniques; Inflammation - genetics; Inflammation - metabolism; Lipopolysaccharides - pharmacology; Mice; Microglia - drug effects; Microglia - metabolism; Nitric Oxide - metabolism; Peptide Fragments - pharmacology; Phagocytosis; Proto-Oncogene Proteins - genetics; PU.1; Rotenone - pharmacology; Staurosporine; Trans-Activators - genetics; Uncoupling Agents - pharmacology; Disease-associated microglia; Anti-inflammatory microglia; PU.1; Alzheimer's disease; Amyloid β; Phagocytosis