Characteristics of Memory B Cells Elicited by a Highly Efficacious HPV Vaccine in Subjects with No Pre-existing Immunity

• Published in: PLoS pathogens Vol. 10; no. 10; p. e1004461
• Main Authors: Scherer, Erin M., Smith, Robin A., Simonich, Cassandra A., Niyonzima, Nixon, Carter, Joseph J., Galloway, Denise A.
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 01.10.2014; Public Library of Science (PLoS)
• Subjects: Adolescent; Antigens; B cells; B-Lymphocytes - virology; Biology and Life Sciences; Communicable Diseases; Female; Health aspects; HIV Infections - virology; HIV-1; Human papillomavirus; Human papillomavirus 16; Humans; Immune response; Immune system; Immunologic Memory - immunology; Immunological research; Medicine and Health Sciences; Papillomavirus Vaccines - therapeutic use; Vaccination - methods; Vaccines; Virus research

Licensed human papillomavirus (HPV) vaccines provide near complete protection against the types of HPV that most commonly cause anogenital and oropharyngeal cancers (HPV 16 and 18) when administered to individuals naive to these types. These vaccines, like most other prophylactic vaccines, appear to...