ABCC5 facilitates the acquired resistance of sorafenib through the inhibition of SLC7A11-induced ferroptosis in hepatocellular carcinoma - Huang, Wenbin; Chen, Kunling; Lu, Yishi; Zhang, Donghui; Cheng, Yuan; Li, Liuran; Huang, Weimei; He, Guolin; Liao, Hangyu; Cai, Lei; Tang, Yujun; Zhao, Liang; et al. (Neoplasia (New York, N.Y.), 2021)
Keywords: ABCC5; Acquired resistance; Amino Acid Transport System y+ - metabolism; Carcinoma, Hepatocellular - metabolism; Carcinoma, Hepatocellular - pathology; Cell Line, Tumor; Drug Resistance, Neoplasm - physiology; Ferroptosis; Ferroptosis - physiology; Hepatocellular carcinoma; Humans; Liver Neoplasms - metabolism; Liver Neoplasms - pathology; Multidrug Resistance-Associated Proteins - metabolism; Original article; Sorafenib; Sorafenib - pharmacology; GPx4; IHC; ABCC5; qRT-PCR; Hepatocellular carcinoma; Ferroptosis; HCC; SLC7A11; Acquired resistance; NRF2; Sorafenib; ROS; IF; GSH; 5-Fu